TY - JOUR T1 - An early prognostic marker for determining disease severity in acute cholangitis: CRP/albumin ratio AU - İnan, Osman AU - Arasan, Sema Nur AU - Şahiner, Enes Seyda AU - Surel, Aziz AU - Altıparmak, Emin AU - Zengin, Oğuzhan AU - Ateş, İhsan PY - 2024 DA - March Y2 - 2024 JF - ACH Medical Journal JO - ACH Med J PB - Ankara Şehir Hastanesi WT - DergiPark SN - 2822-5872 SP - 331 EP - 337 VL - 3 IS - 1 LA - en AB - Introductıon: This study was undertaken to investigate the importance of the CRP/albumin ratio (CAR) as an early prognostic marker for determining disease severity in acute cholangitis.Methods: A total of 366 patients aged >18 years diagnosed with acute cholangitis were included in the study. Acute cholangitis severity was determined according to the 2018 Tokyo criteria.Results: The study population consisted of 49.2% patients with mild, 24.6% moderate, and 26.2% severe acute cholangitis. The cut-off CAR value for predicting moderate risk compared to the mild risk group was found to be >1 with 73.3% sensitivity and 76.7% specificity (AUC±SE: 0.785±0.03; +PV: 61.1%, -PV: 85.2%; p2.9 with 71.9% sensitivity and 71.1% specificity (AUC±SE: 0.788±0.03; +PV: 72.6%, -PV: 70.3%; p2.5 with 77.4% sensitivity and 74.6% specificity (AUC±SE: 0.803±0.03; +PV: 43.1%, -PV: 90.1%; p2.8 with 100% sensitivity and 74.9% specificity (AUC±SE: 0.890±0.03; +PV: 19.5%, -PV: 100%; p KW - Choledocholithiasis KW - Cholestasis KW - Cholangitis KW - Inflammation KW - Tokyo guidelines CR - 1. Sulzer, J.K. & Ocuin, L.M. Cholangitis: causes, diagnosis, and management. Surgical Clinics 99, 175-184 (2019). CR - 2. Endo, I., Takada, T., Hwang, T.L., Akazawa, K., Mori, R., Miura, F. et al. Optimal treatment strategy for acute cholecystitis based on predictive factors: Japan‐Taiwan multicenter cohort study. Journal of Hepato‐Biliary‐Pancreatic Sciences 24, 346-361 (2017). CR - 3. 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