TY  - JOUR
T1  - LİF TÜKETİMİNİN GEBELİKTE KORTİZOL SEVİYELERİ VE HPA AKSINA ETKİSİ
TT  - Effect of Fiber Consumption on Cortisol Levels and HPA Axis in Pregnancy
AU  - Yılmaz, Dursun Alper
AU  - Çağıran, İbrahim Hakkı
AU  - Yıldız, Metin
AU  - Yıldırım, Mehmet Salih
AU  - Dege, Gökhan
PY  - 2024
DA  - April
Y2  - 2024
DO  - 10.5281/zenodo.10929553
JF  - Journal of Midwifery and Health Sciences
JO  - Ebelik ve Sağlık Bilimleri Dergisi
PB  - Ataturk University
WT  - DergiPark
SN  - 2687-2110
SP  - 187
EP  - 194
VL  - 7
IS  - 1
LA  - tr
AB  - Zararlı bir uyaranın algılanması sırasında savaş ya da kaç tepkisine bir adaptasyon olarak gelişen stres, bazı koşullar altında (sinir, endokrin ve bağışıklık sistemleri dahil) zararlı olabilecek bir dizi fizyolojik tepkiyi uyarır. Bu tepkiler arasında hipotalamus- hipofiz- adrenal aksının hiperaktivitesi, depresif hastalarda en yaygın görülen nörobiyolojik değişikliklerden biridir. Özellikle gebelikte depresyon, ruh sağlığını tehlikeye atan sinsi bir halk sağlığı sorunudur. Ciddiye alınmadığı durumlarda intihara kadar giden vakalar ile karşılaşılabilmektedir. Doğum öncesi depresyonun olumsuz sonuçları yalnız annede değil, ileri dönemde çocuk üzerinde de görülmektedir. Gebeliğe bağlı depresyon, genellikle birden çok sebebe bağlı olup birçok farklı fizyolojik etkenle ilişkilidir. Hamilelik sırasında ortaya çıkan fizyolojik kaymalar, maternal stres koruma mekanizmasında hipotalamus- hipofiz- adrenal aksı düzensizliği ve kortizolün aşırı salgılanması gibi değişikliklerin oluşmasına sebep olur. Vücudun strese gösterdiği tepkiyle ilişkili olan aşırı kortizol salınımı, gebelik süresince görülen depresif belirtilerle ilişkilidir. Yakın zamanda yapılan çalışmalar belirli diyet etkenlerinin özellikle diyet liflerinin, stres hormonunu zayıflattığını vurgulamaktadır. Vücuda alınan diyet lifi, bağırsak bakterileri vasıtasıyla sindirilir ve kısa zincirli yağ asitlerinin ortaya çıkarılmasını sağlar. Söz konusu metabolitlerin hipotalamus- hipofiz- adrenal aksı başta olmak üzere pek çok değişik nörolojik fonksiyonu etkilediği düşünülmektedir. Bu derleme makale, kortizol salınımnda rol oynadığı düşünülen lif tüketiminin yaptığı değişiklikleri belirlemeyi hedeflemektedir
KW  - depresyon
KW  - diyet posası
KW  - gebelik
KW  - pituiter-adrenal sistem
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UR  - https://doi.org/10.5281/zenodo.10929553
L1  - https://dergipark.org.tr/en/download/article-file/3830001
ER  -