@article{article_1473675, title={Prevalence of Dens Invaginatus: Systematic Review and Meta-Analysis}, journal={Acta Odontologica Turcica}, volume={42}, pages={131–140}, year={2025}, author={Çakıcı, Fatih and Çakıcı, Elif and Mutlu, Seca and Ünal, Mert}, keywords={CBCT, Dental anomalies, Dens Invaginatus, periapical radiograph, Prevalence.}, abstract={This systematic review and meta-analysis aims to determine the prevalence of dens invaginatus (DI) by evaluating studies of DI prevalence using cone beam computed tomography (CBCT) and two-dimensional radiography. It also compares the effects of CBCT and two-dimensional radiography in determining the prevalence of DI. Our study was conducted following PRISMA statements. The MeSH terms and keywords were used to search articles published in three electronic databases PubMed, Web of Science, and Scopus. In addition, the bibliographic references of the qualifying papers were manually searched. The search strategy was limited to English and Turkish articles published before 12 December 2022. Data was collected according to inclusion and exclusion criteria. The included studies were assessed by two independent reviewers using Joanna Briggs Institute’s critical appraisal checklist for the prevalence studies. Thirty-one studies were included in this meta-analysis. Patients (51626) and teeth (127998) were examined in the included studies. The prevalence of patients with DI and the prevalence of teeth with DI are 0,028(CI 0,017-0,045) and 0,011(0,006-0,020) respectively. The mean effect size is 0,065(CI 0,033-0,122) for the CBCT method and 0,019(CI 0,010-0,021) for the two-dimensional radiography. The meta-regression shows that there is a statistical difference between CBCT and two-dimensional radiography methods (p =0,0259). Clinicians are likely to encounter DI many times. Therefore, an early identification and correct management of affected teeth is essential for improving the prognosis of these teeth. Additionally, there is a statistical difference between determining methods (CBCT and two- dimensional methods) of DI. Registration: PROSPERO (CRD42023442411).}, number={3}, publisher={Gazi University}