@article{article_1482798, title={Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio Changes During Follow-up in Celiac Patients}, journal={Akdeniz Tıp Dergisi}, volume={11}, pages={261–265}, year={2025}, DOI={10.53394/akd.1482798}, author={Gülseren, Arzu and Gulcu Taskin, Didem}, keywords={Neutrophil to lymphocyte ratio, Celiac Patients, Platelet to lymphocyte ratio}, abstract={Aim: Compare the Neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) ratios of pre-diagnosis and diet-adherent follow-up patients with Celiac disease (CD) and to evaluate the cost-effective parameters that can be used in future follow-up. Methods: Patients admitted to the Pediatric Gastroenterology clinic between 2020 and 2023 and diagnosed with celiac disease were retrospectively analyzed for the study. Patients with heart failure, peripheral vascular disease, acute or chronic infection, cancer, hematologic, liver disease and chronic drug use (nonsteroidal anti-inflammatory, anticoagulant) were excluded. Results: A total of 287 patients were included in the study. After treatment, the control complete blood count value was checked at the earliest 3 months and at the latest 10 months (mean 5.4 ± 1.6 months). Neutrophil values showed a significant decrease in CD patients on gluten-free diet. The mean platelet value decreased during follow-up, but the result was not significant. It was analyzed that lymphocyte values increased with gluten free diet. Pre-diagnosis and follow-up NLR (2.4 ± 1.3 vs 1.9 ± 1.1; P < 0.001) and PLR (141 ± 65 vs 119 ± 56; P < 0.001) values of CD patients treated with gluten-free diet showed a significant decrease. Conclusion: NLR, PLR rates decrease during follow-up in CD patients adhering to a gluten-free diet. It may be possible to follow-up celiac disease with NLR and PLR values obtained from complete blood count, which are low cost and routinely used.}, number={2}, publisher={Akdeniz University}