@article{article_1489736, title={Polymicrobial Infections in Fournier’s Gangrene: A Case Report and Review of Management Strategies}, journal={Tıp Fakültesi Klinikleri Dergisi}, volume={8}, pages={61–65}, year={2025}, author={Özdemir, Serdar and Algın, Abdullah}, keywords={Fournier, Necrotizing fasciitis, Multidisciplinary management, Polymicrobial infection, Surgical debridement}, abstract={Fournier’s gangrene is a rapidly progressing necrotizing fasciitis affecting the perineal, perianal, and genital regions. It is a life-threatening condition that requires prompt diagnosis and aggressive treatment. This case report describes an 82-year-old male with multiple comorbidities, including inoperable colon cancer, COPD, hypertension, and diabetes, who presented with severe testicular pain and systemic symptoms. Initial treatment included broad-spectrum antibiotics and extensive surgical debridement. The patient underwent multiple debridement and skin grafting for scrotal reconstruction. Perioperative cultures identified polymicrobial infection, including Pseudomonas aeruginosa and Escherichia coli. The patient’s condition improved with tailored antibiotic therapy and supportive care, leading to discharge after 38 days. Early recognition and a multidisciplinary approach are crucial for managing Fournier’s gangrene, given its high mortality rate. This case highlights the importance of comprehensive care in improving patient outcomes}, number={1}, publisher={Istanbul Aydin University}