@article{article_1517834, title={Evaluation of iron, iron binding capacity, transferrin, some oxidative stress markers and hematological parameters in foot and mouth disease in cattle}, journal={Mediterranean Veterinary Journal}, volume={9}, pages={224–229}, year={2024}, DOI={10.24880/meditvetj.1517834}, author={Sezer, Mert and Gezer, Tahir and Merhan, Oğuz and Akyüz, Enes and Bozukluhan, Kadir and Gökce, Gürbüz}, keywords={cattle, foot and mouth disease, oxidative stress, transferrin}, abstract={This study aimed to investigate the changes in serum iron, iron binding capacity, transferrin, some oxidative stress markers, and hematological and biochemical parameters in cattle infected with foot-and-mouth disease and to reveal their importance. The animal material of the study was composed of 20 Simmental cattle between 6 and 12 months of age, which were diagnosed with foot-and-mouth disease based on the results of the clinical and laboratory examinations (patient group), and the control group was composed of 10 animals selected from a different herd, with the same age group and breed characteristics and fed with the same ration. Among the hematological parameters examined in the study, the total leukocyte count (WBC (x103/μL)) was found to be higher in the patient group with statistical significance compared to the control group (P <0.05). Among the biochemical parameters, iron (Fe (μg/dL)), total iron binding capacity (TIBC (μg/dL)), phosphorus (P (mg/dl)), magnesium (Mg (mg/dl)), and glucose (mg/dl) ) levels were found to be significantly lower (P <0.001); the transferrin saturation (TS (%)), reduced glutathione (GSH (mg/dL)), and alkaline phosphatase (ALP (U/L)) were found to be significantly lower (P <0.05); and Malondialdehyde (MDA (μmol/L)), creatine kinase (CK ((U/L)), and creatinine (Crea (mg/dl)) were found to be significantly higher (P <0.05) in the patient group compared to the control group. Consequently among the biochemical parameters examined in the study, the changes in the Fe (μg/dL), TIBC (μg/dL), TS (%), GSH (mg/dL), and MDA (μmol/L) levels were observed.}, number={1}, publisher={Burdur Mehmet Akif Ersoy University}