TY - JOUR T1 - A CASE REPORT OF GALLBLADDER CANCER IN A 17-YEAR OLD PATIENT: DIAGNOSTIC CHALLENGES AND SURGICAL MANAGEMENT TT - ON YEDİ YAŞINDAKİ BİR HASTADA SAFRA KESESİ KANSERİ OLGUSU: TANISAL ZORLUKLAR VE CERRAHİ TEDAVİ AU - Jaradat, Jaber H. AU - Naser, Ayman AU - Al Asbahi, Hanan M. AU - Aljahmi, Abdulmajeed Abulkhair PY - 2025 DA - January Y2 - 2024 DO - 10.26650/IUITFD.1529167 JF - Journal of Istanbul Faculty of Medicine JO - İst Tıp Fak Derg PB - Istanbul University WT - DergiPark SN - 1305-6441 SP - 83 EP - 87 VL - 88 IS - 1 LA - en AB - Gallbladder cancer is a rare and aggressive malignancy with a poor prognosis, often diagnosed incidentally or at an advanced stage. This case study demonstrates an uncommon clinical entity of Gallbladder cancer in a 17-year-old male. The patient was presented with generalised abdominal pain and leukocytosis and mildly elevated liver enzymes. Initial imaging showed no gallstones; however, subsequent ultrasonography revealed an intraluminal hyperechoic lesion in the gallbladder. Laparoscopic cholecystectomy and biopsy confirmed well-differentiated adenocarcinoma without lymphovascular or perineural invasion. On follow-up, no complication was reported. In this case report, we highlight the importance of considering Gallbladder cancera differential diagnosis after excluding the most common aetiologies at the young age group. KW - Gallbladder cancer KW - cancer KW - young age N2 - Safra kesesi kanseri, genellikle tesadüfen veya ileri evrede teşhis edilen, kötü prognozlu nadir ve agresif bir malignitedir. Bu olgu sunumunda, 17 yaşında bir erkek hastada nadir görülen bir safra kesesi kanseri olgusu sunulmaktadır. Yaygın karın ağrısı, lökositoz ve karaciğer enzimlerinde hafif artış sebebiyle başvurmuştu. İlk yapılan görüntülemede safra kesesinde taş görülmedi ancak daha sonraki ultrasonografide safra kesesinde intraluminal hiperekoik bir lezyon saptandı. Laparoskopik kolesistektomi uygulanan hastada patolojik incelemede lenfovasküler veya perinöral invazyon göstermeyen iyi farklılaşmış adenokarsinom saptandı. Takipte herhangi bir komplikasyon görülmedi. Bu olgu sunumunda, genç yaş grubunda en yaygın etiyolojileri dışladıktan sonra safra kesesi kanserini ayırıcı tanı olarak düşünmenin önemini vurguluyoruz. CR - Halaseh SA, Halaseh S, Shakman R. A Review of the Etiology and epidemiology of gallbladder cancer: what you need to know. Cureus 2024;14(8):e28260. google scholar CR - Lazcano-Ponce EC, Miquel JF, Munoz N, Herrero R, Ferrecio C, Wistuba II, et al. Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin 2001;51(6):349-64. [CrossRef] google scholar CR - Sulieman I, Elmoghazy W, El Ansari W, Elaffandi A, Khalaf H. Gallbladder cancer: 7-Year experience from Qatar. Ann Med Surg (Lond) 2019;44:33-8. [CrossRef] google scholar CR - Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68(6):394-424. [CrossRef] google scholar CR - Rawla P, Sunkara T, Thandra KC, Barsouk A. Epidemiology of gallbladder cancer. Clin Exp Hepatol 2019;5(2):93-102. [CrossRef] google scholar CR - Andren-Sandberg Â. Diagnosis and Management of Gallbladder Cancer. N Am J Med Sci 2012;4(7):293-9. [CrossRef] google scholar CR - Muduly DK, Satyanarayana Deo SV, Shukla NK, Kallianpur AA, Prakash R, Jayakrishnan T. Gall bladder cancer in a child: a rare occurrence. J Cancer Res Ther 2012;8(4):653-4. [CrossRef] google scholar CR - Al Manasra AR, Bani Hani M, Qandeel H, Al Asmar S, Alqudah M, Al-Zoubi N, et al. Trends of gallbladder cancer in jordan over 2 decades: where are we? Clin Med Insights Case Rep 2018;11:1179547618771699. [CrossRef] google scholar UR - https://doi.org/10.26650/IUITFD.1529167 L1 - https://dergipark.org.tr/en/download/article-file/4126775 ER -