TY - JOUR T1 - Evaluation of Factors Affecting Survival and Chemotherapy Regimens in Patients with Gastric Cancer AU - Özer Aydın, Çağlar AU - Aydın, Hüsnü AU - Dursun, Nevra AU - Gürsu, Rıza Umar PY - 2025 DA - April Y2 - 2024 DO - 10.31067/acusaglik.1530956 JF - Acıbadem Üniversitesi Sağlık Bilimleri Dergisi JO - Acibadem Univ Saglik Bilim Derg PB - Acibadem Mehmet Ali Aydinlar University WT - DergiPark SN - 1309-470X SP - 240 EP - 245 VL - 16 IS - 2 LA - en AB - Background/Purpose: The aim of our study was to examine the factors that affect the prognosis of gastric cancer and to evaluate the effect of different chemotherapy regimens on disease-free survival and overall survival.Methods: This cohort study retrospectively analyzed patients diagnosed with gastric cancer at our institution between 2009 and 2013. The demographic characteristics of the patients, the presence of Helicobacter pylori (HP), and the disease-free and overall survival according to the patients' treatment protocols were examined.Results: Thirty-three women and 85 men with a mean age of 58.6 ± 10.3 years were included in this study. %41 of the patients received 5-fluouracil, leukoverine chemotherapy (MAYO regimen), 26.2% docetaxel, cisplatin and fluorouracil combination (DCF regimen), 10.7% Epirubicin, cisplatin and Fluorouracil (ECF regimen), and 6.6% Cisplatin-Xeloda regimen. The average disease-free survival was 14.7 ± 11.1 months, and overall survival time was 16.5 ± 11.4 months. Disease-free survival and overall survival were longer in the MAYO regimen group compared to the combination chemotherapy groups (p KW - Chemotherapy KW - Gastric cancer KW - Survival CR - 1- Jemal, A., Siegel, R., Xu, J, et al. Cancer statistics.CA a cancer journal for clinicians. 2010; 60(5), 277:300. 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UR - https://doi.org/10.31067/acusaglik.1530956 L1 - https://dergipark.org.tr/en/download/article-file/4134767 ER -