TY  - JOUR
T1  - Rare Side Effect of Immune Checkpoint Inhibitors: Adrenal Insufficiency
TT  - İmmün Checkpoint İnhibitörlerinin Nadir Yan Etkisi: Adrenal Yetmezlik
AU  - Yolacan, Ramazan
AU  - Kaya, Bekir
AU  - Üzel, Ali
AU  - Karabulut, Ümit
AU  - Uçmak, Feyzullah
AU  - Kaya, Muhsin
PY  - 2025
DA  - March
Y2  - 2025
DO  - 10.35440/hutfd.1546792
JF  - Harran Üniversitesi Tıp Fakültesi Dergisi
PB  - Harran University
WT  - DergiPark
SN  - 1304-9623
SP  - 195
EP  - 198
VL  - 22
IS  - 1
LA  - en
AB  - SummaryImmune checkpoint inhibitors are cell membrane proteins that regulate the immune response.  It is used in the treatment of non-small cell lung cancer, renal cell carcinoma, melanoma and some other tumor types. They affect the dermatological, gastrointestinal, hepatic, endocrine and other systems.  We present a case of adrenal insufficiency caused by nivolumab in a patient presenting with complaints of weakness, fatigue, nausea and vomiting.
KW  - Adrenal insufficiency
KW  - Nivolumab
KW  - Immune checkpoint inhibitors
N2  - Amaç: İmmün kontrol noktası inhibitörleri immun yanıtı düzenleyen hücre zar proteinleridir. Küçük hücreli dışı akciğer kanseri, renal hücreli karsinom, melanom ve diğer bazı tümör tiple-rinin tedavisinde kullanılmaktadır. Dermatolojik, gastrointestinal, hepatik, endokrin ve diğer sistemleri etkilerler. Halsizlik, yorgunluk, bulantı ve kusma şikâyetleri ile başvuran bir hasta-da nivolumabın neden olduğu adrenal yetmezlik olgusunu sunuyoruz.
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UR  - https://doi.org/10.35440/hutfd.1546792
L1  - https://dergipark.org.tr/en/download/article-file/4202447
ER  -