TY  - JOUR
T1  - Investigation of Swelling Capacity of Carboxymethyl Cellulose/Gelatin/Zinc Oxide Hydrogels
AU  - Tamahkar Irmak, Emel
AU  - Arıkan, Ezgi
AU  - Çiçek Kocabaş, Ecem
AU  - Nuray, Batuhan
AU  - Efecan, Aleyna Tuğçe
AU  - Ciğeroğlu, Zeynep
PY  - 2025
DA  - October
Y2  - 2024
DO  - 10.15671/hjbc.1547339
JF  - Hacettepe Journal of Biology and Chemistry
JO  - HJBC
PB  - Hacettepe University
WT  - DergiPark
SN  - 2687-475X
SP  - 11
EP  - 19
VL  - 53
IS  - 4
LA  - en
AB  - Carboxymethyl cellulose (CMC)-based hydrogels had great potential in biomedical applications due to their biodegradability, biocompatibility, and solubility. Gelatin-based hydrogels were significant in the biomedical field for applications due to their high water retention capacity, biocompatibility, and biodegradability. Zinc oxide nanoparticles (ZnO) presenting high biocompatibility are widely used as an antimicrobial agent. CMC/Gelatin/ZnO hydrogels were developed with different ZnO nanoparticle ratios (0.05%, 0.1%) with further crosslinking using glutaraldehyde (1%, 2%, 2.5%, and 5%). The aim of this study was to investigate the effect of pH (pH: 5.5; 7.5) on the swelling behaviour of CMC/Gelatin/ZnO hydrogels. The increase in ZnO content resulted in the increase of swelling capacity. The highest swelling percentage (670%) occurred at pH 5.5 with the samples containing 0.1% ZnO. The lowest swelling ratio (467%) was observed at the pH 5.5 with the control group.
KW  - Carboxymethyl cellulose
KW  - gelatin
KW  - Zinc oxide
KW  - swelling
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UR  - https://doi.org/10.15671/hjbc.1547339
L1  - https://dergipark.org.tr/en/download/article-file/4203658
ER  -