@article{article_1552492, title={Effect of Hypochlorous Acid on Acrylic Resins in Preventing Cross-infection Between Clinic and Laboratory}, journal={Clinical and Experimental Health Sciences}, volume={15}, pages={226–231}, year={2025}, DOI={10.33808/clinexphealthsci.1552492}, author={Basmacı, Fulya and Uslu Akçam, Özge and Özcivelek, Tuğgen}, keywords={Acrylic resin, COVID-19, Disinfectants, Hypochlorous acid, Infection control}, abstract={Objective: The COVID-19 pandemic and monkeypox disease have highlighted the importance of preventing cross-infection between dental laboratories and clinics. Thus, the aim of this study was to evaluate the effects of hypochlorous acid (HOCL), a natural disinfectant that is effective on bacteria and viruses, on polymethylmetacrylate (PMMA) to prevent cross-infection. Methods: A total of 120 PMMA (60 heat-activated and 60 three dimensionally printed) samples were prepared. The samples were immersed in HOCL and ortophtalaldehyde (OPA) disinfectant twice for 30 minutes to simulate the travel time to clinic and the dental laboratory. 10 samples from each group were kept in deionized water as a control group. Flexural strength and surface roughness measurements of the samples were performed. T-test and Kruskal Wallis H test were used for statistical evaluation (α=0.05). Results: There was no significant difference in flexural strength or Ra values between the HOCL and OPA groups. Conclusion: HOCL PMMA may be considered an alternative disinfectant for preventing cross-infection between dental laboratories and clinics in dentures and orthodontic appliances. Further research is required to evaluate its biological efficacy and long-term use.}, number={1}, publisher={Marmara University}