TY  - JOUR
T1  - Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children
TT  - Çocukluk Çağı Brusellozuna İlişkin Osteoartiküler Tutulumun Değerlendirilmesi
AU  - Bekis Bozkurt, Hayrunnisa
AU  - Kutlu Beşeren, Tuğba Nur
AU  - Ergüven, Müferet
AU  - Bıçakçı, Zafer
PY  - 2025
DA  - April
Y2  - 2025
DO  - 10.18678/dtfd.1579167
JF  - Duzce Medical Journal
JO  - Duzce Med J
PB  - Duzce University
WT  - DergiPark
SN  - 1307-671X
SP  - 75
EP  - 80
VL  - 27
IS  - 1
LA  - en
AB  - Aim: Brucellosis is a significant public health problem with high morbidity. Its most frequent complication is osteoarticular involvement. The study aimed to evaluate the relationship of osteoarticular involvement with clinical features and prognosis in children with brucellosis.Material and Methods: This retrospective study included pediatric patients between the ages of 1 and 18 years who were hospitalized and diagnosed with brucellosis between 2015 and 2020, and were regularly followed up. and all their findings and osteoarticular involvement data within the last two years were recorded. Clinical features, laboratory findings, osteoarticular involvement, and relapse rates of the patients were evaluated.Results: A total of 80 patients were included study. During the follow-up period, relapse developed in 14 (17.5%) patients. The most commonly affected joints were right (40%, n=32) and left (26.3%, n=21) hips, then right (27.5%, n=22) and left (23.8%, n=19) knees. Shoulder joint involvement rates and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT), and aspartate aminotransferase (AST) levels were statistically significantly higher in the relapse group (p=0.016, p=0.003, p=0.001, p
KW  - brucellosis
KW  - osteoarthritis
KW  - sacroiliac joint
KW  - shoulder joint
KW  - relapse
N2  - Amaç: Bruselloz, yüksek morbiditeye sahip önemli bir halk sağlığı sorunudur. En sık görülen komplikasyonu osteoartiküler tutulumdur. Bu çalışmanın amacı, bruselloz tanılı çocuklarda osteoartiküler tutulumun klinik özellikler ve prognoz ile ilişkisini değerlendirmektir.Gereç ve Yöntemler: Geriye dönük bu çalışmaya, 2015 ve 2020 yılları arasında bruselloz tanısıyla hastaneye yatırılan ve düzenli takipleri yapılan 1 ile 18 yaş aralığındaki pediatrik hastalar dahil edildi. Son iki yıldaki tüm bulguları ve osteoartiküler tutulum verileri kaydedildi. Hastaların klinik özellikleri, laboratuvar bulguları, osteoartiküler tutulum ve nüks oranları değerlendirildi.Bulgular: Çalışmaya toplam 80 hasta dahil edildi. Takip süresinde hastaların 14 (%17,5) hastada relaps gelişti. En sık etkilenen eklemler sağ (%40, n=32) ve sol (%26,3, n=21) kalçalar, ardından sağ (%27,5, n=22) ve sol (%23,8, n=19) dizlerdi. Omuz eklem tutulum oranları ile C-reaktif protein (CRP), eritrosit sedimantasyon hızı (ESH), alanin transaminaz (ALT) ve aspartat aminotransferaz (AST) düzeyleri relaps grubunda istatistiksel olarak anlamlı şekilde daha yüksekti (sırasıyla p=0,016, p=0,003, p=0,001, p
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UR  - https://doi.org/10.18678/dtfd.1579167
L1  - https://dergipark.org.tr/en/download/article-file/4339007
ER  -