TY  - JOUR
T1  - Neuropathic Pain in Lumbar Disc Herniation: A Comparative Study of Surgical Outcomes
TT  - Lomber Disk Hernisinde Nöropatik Ağrı: Cerrahi Sonuçların Karşılaştırmalı Bir Çalışması
AU  - Şanlı, Zeynep Selcan
AU  - Yılmaz, Ahmet
PY  - 2024
DA  - December
Y2  - 2024
DO  - 10.36516/jocass.1586642
JF  - Journal of Cukurova Anesthesia and Surgical Sciences
JO  - J Cukurova Anesth Surg
PB  - Merthan TUNAY
WT  - DergiPark
SN  - 2667-498X
SP  - 247
EP  - 250
VL  - 7
IS  - 4
LA  - en
AB  - Background: This study aimed to assess the prevalence of neuropathic pain in patients diagnosed with lumbar disc herniation and to examine the correlation between neuropathic pain and surgical intervention.Material and methods: We performed a retrospective cohort study involving 217 patients diagnosed with lumbar disc herniation who reported persistent low back pain from January to December 2023. We assessed the existence of neuropathic pain using the Douleur Neuropathique 4 (DN4) questionnaire. We evaluated pain severity using the Visual Analogue Scale (VAS). We categorized the patients into three groups: non-operated, operated without stabilization, and operated with stabilization.Results:The patients had a mean age of 45.09 ± 14.28 years, with 57.6% being male. A DN4 score of > 4 indicated that neuropathic pain was present in more than half (51.2%) of the patients. The prevalence of neuropathic pain was 32.8% in the non-operated cohort, 67.3% in the operated cohort without stabilization, and 85% in the operated cohort with stabilization. Age exhibited a positive link with neuropathic pain score (r = 0.16, p
KW  - chronic low back pain
KW  - lumbar disc herniation
KW  - neuropathic pain
CR  - 1.Zou T, Liu XY, Wang PC, et al. Incidence of Spontaneous Resorption of Lumbar Disc Herniation: A Meta-analysis. Clin Spine Surg. 2024;37(6):256-269. 
https://doi.org/10.1097/BSD.0000000000001490
CR  - 2.Çalık Y, Çalık AF. Kronik Bel Ağrılı Hastalarda Nöropatik Ağrının Fonksiyonel Yetersizlik Üzerine Etkisinin Değerlendirilmesi. Turk J Osteoporos. 2015;21(3): 122-6. 
https://doi.org/10.4274/tod.87160
CR  - 3.Ostafiński K, Świątnicki W, Szymański J, et al. Predicting conservative treatment failure in patients with lumbar disc herniation. Single center, case-control study. Clin Neurol Neurosurg. 2020;193:105867.
https://doi.org/10.1016/j.clineuro.2020.105867
CR  - 4.Shimony N, Louie C, Barrow D, et al. Adolescent Disc Disease: Risk Factors and Treatment Success-Related Factors. World Neurosurg. 2021;148:e314-e320. 
https://doi.org/10.1016/j.wneu.2020.12.126
CR  - 5.Karcioglu O, Topacoglu H, Dikme O, Dikme O. A systematic review of the pain scales in adults: Which to use? Am J Emerg Med. 2018;36(4):707-14. https://doi.org/10.1016/j.ajem.2018.01.008
CR  - 6.Attal N, Perrot S, Fermanian J, Bouhassira D. The neuropathic components of chronic low back pain: a prospective multicenter study using the DN4 Questionnaire. J Pain. 2011;12(10):1080-7.
https://doi.org/10.1016/j.jpain.2011.05.006
CR  - 7.Baron R, Binder A, Attal N, Casale R, Dickenson AH, Treede RD. Neuropathic low back pain in clinical practice. Eur J Pain Lond Engl. 2016;20(6):861-73. https://doi.org/10.1002/ejp.838
CR  - 8.Yakşi E, Ketenci A, Baslo MB, Orhan EK. Does transcutaneous electrical nerve stimulation affect pain, neuropathic pain, and sympathetic skin responses in the treatment of chronic low back pain? A randomized, placebo-controlled study. Korean J Pain. 2021;34(2):217-28.
https://doi.org/10.3344/kjp.2021.34.2.217
CR  - 9.Mehra M, Hill K, Nicholl D, Schadrack J. The burden of chronic low back pain with and without a neuropathic component: a healthcare resource use and cost analysis. J Med Econ. 2012;15(2):245-52.
https://doi.org/10.3111/13696998.2011.642090
CR  - 10.Freynhagen R, Baron R, Tölle T, et al. Screening of neuropathic pain components in patients with chronic back pain associated with nerve root compression: a prospective observational pilot study (MIPORT). Curr Med Res Opin. 2006;22(3):529-37.
https://doi.org/10.1185/030079906X89874
CR  - 11.Kaki AM, El-Yaski AZ, Youseif E. Identifying neuropathic pain among patients with chronic low-back pain: use of the Leeds Assessment of Neuropathic Symptoms and Signs pain scale. Reg Anesth Pain Med. 2005;30(5):422-8. 
https://doi.org/10.1016/j.rapm.2005.05.013
CR  - 12.Sakai Y, Ito K, Hida T, Ito S, Harada A. Neuropathic Pain in Elderly Patients with Chronic Low Back Painand Effects of Pregabalin: A Preliminary Study. Asian Spine J. 2015;9(2):254-62.
https://doi.org/10.4184/asj.2015.9.2.254
CR  - 13.Shiri R, Falah-Hassani K, Heliövaara M, et al. Risk Factors for Low Back Pain: A Population-Based Longitudinal Study. Arthritis Care Res. 2019;71(2):290-9. 
https://doi.org/10.1002/acr.23710
CR  - 14.Siddiqui AS, Javed S, Abbasi S, Baig T, Afshan G. Association Between Low Back Pain and Body Mass Index in Pakistani Population: Analysis of the Software Bank Data. Cureus. 14(3):e23645.
https://doi.org/10.7759/cureus.23645
CR  - 15.Ulutaş M, ÇInar K, Seçer M. The surgery and early postoperative radicular pain in cases with multifocal lumbar disc herniation. Medicine (Baltimore). 2017;96(9):e6238. 
https://doi.org/10.1097/MD.0000000000006238
CR  - 16.Akgün AS, Ağirman M. Neuropathic Pain and Disability in Patients with Lumbar Spinal Stenosis. Turk J Geriatr. 2018;21(1):56-61. https://doi.org/10.31086/tjgeri.2018137967
CR  - 17.Karaci̇f D, Bölükbaşi A. Evaluation of Neuropathic Pain Frequency and Related Factors in Patients with Chronic Low Back Pain. Fiz Tıp Ve Rehabil Bilim Derg. 2022;25(3):332-8. 
https://doi.org/10.31609/jpmrs.2022-89033
CR  - 18.Dolgun H, Turkoglu E, Kertmen H, et al. Gabapentin versus pregabalin in relieving early post-surgical neuropathic pain in patients after lumbar disc herniation surgery: a prospective clinical trial. Neurol Res. 2014;36(12):1080-5. 
https://doi.org/10.1179/1743132814Y.0000000404
UR  - https://doi.org/10.36516/jocass.1586642
L1  - https://dergipark.org.tr/en/download/article-file/4372324
ER  -