@article{article_1589393, title={Development of IrO2 Nanoparticles-Based Lateral Flow Immunosensor for Determination of Parathyroid Hormone}, journal={Necmettin Erbakan Üniversitesi Fen ve Mühendislik Bilimleri Dergisi}, volume={7}, pages={286–293}, year={2025}, author={Gümüş, Eda and Bingöl, Haluk and Zor, Erhan}, keywords={Lateral flow immunosensor, Paper-based biosensor, Iridium oxide nanoparticle, Parathyroid hormone}, abstract={The conveniences that biosensors bring to our lives pave the way for new studies that will enable biosensor technology to develop day by day. Qualitative and quantitative analyses are conducted in many areas with optical sensors. Among these areas, hormone tests, which are important in terms of health, also attract attention. This study aims to detect parathyroid hormone (PTH), which has an important role in some metabolic activities by maintaining calcium balance in the blood, by paper-based lateral flow analysis. PTH levels in the blood are important for the diagnosis of many parathyroid-related diseases and cancer. PTH was determined by the developed iridium oxide nanoparticles-based (IrO2NPs) LFA. At the same time, this is the first study to develop an LFA for the detection of PTH using IrO2NPs. The limit of detection and quantification (LOD and LOQ) of IrO2NPs-based LFA designed for PTH determination were calculated as 3.92 ng/mL and 11.88 ng/mL, respectively.}, number={2}, publisher={Necmettin Erbakan University}, organization={Necmettin Erbakan University, Scientific Research Projects Coordination Unit (NEU-BAP)}