TY - JOUR T1 - Astımın Patogenezi TT - Pathogenesis of Asthma AU - Barlan, Işıl B. AU - Başaran, Müjdat M. PY - 2000 DA - December JF - Türk Pediatri Arşivi PB - TÜRK PEDİATRİ KURUMU DERNEĞİ WT - DergiPark SN - 1306-0015 VL - 35 IS - 4 LA - tr AB - SummaryBronchial asthma is characterized by reversible airway obstruction in response to allergen chronic eosinophilic airway inflammation and nonspecific airway hyperreponsiveness Allergic reaction appears to be the result of a TH2 type T cell response to one or more common environmental allergens The allergen specific TH2 response represents the triggering event for the recruitment and the involvement of the other cell types as well as a large number of soluble factors and adhesion molecules thus result in an inflammatory cascade of unequaled complexity Key words: Asthma Bronchiale Pathogenesis N2 - Bronchial asthma is characterized by reversible airway obstruction in response to allergen chronic eosinophilic airway inflammation and nonspecific airway hyperreponsiveness Allergic reaction appears to be the result of a TH2 type T cell response to one or more common environmental allergens The allergen specific TH2 response represents the triggering event for the recruitment and the involvement of the other cell types as well as a large number of soluble factors and adhesion molecules thus result in an inflammatory cascade of unequaled complexity Key words: Asthma Bronchiale Pathogenesis UR - https://dergipark.org.tr/en/pub/tpedar/issue//159736 ER -