TY  - JOUR
T1  - COMPARISON OF THE ANTIBACTERIAL EFFICIENCY OF SUPER ANIONIC OXYGEN SOLUTION CONTAINING SILVER NANOPARTICLES (NPAG) AND SUPER ANIONIC OXYGEN SOLUTION (H2O8) AGAINST E. FAECALIS AND S. MUTANS – AN IN VITRO STUDY
TT  - GÜMÜŞ NANOPARTİKÜLLERİ İÇEREN SÜPER ANYONİK OKSİJEN SOLÜSYONU (NPAG) İLE SÜPER ANYONİK OKSİJEN SOLÜSYONU’NUN (H2O8) E. FAECALİS VE S. MUTANS'A KARŞI ANTİBAKTERİYEL ETKİNLİĞİNİN KARŞILAŞTIRILMASI – İN VİTRO ÇALIŞMA
AU  - Göçmen, Damla
AU  - Erol, Hilal Basak
AU  - Zıraman, Fatma Gül
AU  - Kaşkatepe, Banu
PY  - 2025
DA  - September
Y2  - 2025
DO  - 10.33483/jfpau.1601950
JF  - Journal of Faculty of Pharmacy of Ankara University
JO  - J. Fac. Pharm. Ankara
PB  - Ankara University
WT  - DergiPark
SN  - 1015-3918
SP  - 785
EP  - 789
VL  - 49
IS  - 3
LA  - en
AB  - Objective: The purpose of this study is to compare the antimicrobial effect of super anionic oxygen solution containing silver nanoparticles (NpAg) and super anionic oxygen solution (H2O8) in vitroMaterial and Method: “The antimicrobial activity of the solutions was tested against Enterococcus faecalis ATCC 29212 (E. faecalis) and Streptococcus mutans ATCC 25175 (S. mutans) standart bacteria. The effects of them applied on the bacterial suspension after 10 minutes were examined in terms of colony reduction.Result and Discussion: As a result of the efficacy tests, NpAg solution showed a 46.67% (0.27 log) decrease in E. faecalis concentration and a 58.8% (0.38 log) decrease in S. mutans concentration. Similarly, H2O8 solution showed an 84.67% (0.81 log) decrease in E. faecalis concentration and a 62.94% (0.43 log) decrease in S. mutans concentration. Under the limitations of this study, it was concluded that super anionic oxygen solutions (NpAg) and super anionic oxygen solutions (H2O8) have a significant antimicrobial flora against E. faecalis and S. mutans, but are attenuated when compared to irrigants routinely used clinically. Since this study did not simulate the oral environment, future studies may provide more effective results.
KW  - Biofilms
KW  - dentin
KW  - endodontics
KW  - nanoparticles
KW  - root canal irrigants
N2  - Amaç: Bu çalışmanın amacı gümüş nanopartikülleri içeren süper anyonik oksijen solüsyonu (NpAg) ile süper anyonik oksijen solüsyonu (H2O8) antimikrobiyal etkisini karşılaştırmaktır.Gereç ve Yöntem: Solüsyonların antimikrobiyal aktivitesi Enterococcus faecalis ATCC 29212 (E. faecalis) ve Streptococcus mutans ATCC 25175 (S. mutans) standart bakterilere karşı test edilmiştir. Bakteri süspansiyonuna 10 dakika sonra uygulananların koloni azalması açısından etkileri incelenmiştir.Sonuç ve Tartışma: Yapılan etkinlik testleri sonucunda NpAg solüsyonu, E. faecalis konsantrasyonunda %46.67 (0.27 log), S. mutans konsantrasyonunda ise %58.8 (0.38 log) azalma gösterdi. Benzer şekilde H2O8 solüsyonu, E. faecalis konsantrasyonunda %84.67 (0.81 log) azalma ve S. mutans konsantrasyonunda %62.94 (0.43 log) azalma gösterdi. Bu çalışmanın sınırlamaları altında, süper anyonik oksijen çözeltilerinin (NpAg) ve süper anyonik oksijen çökeltilerinin (H2O8) E. faecalis ve S. mutans'a karşı önemli bir antimikrobiyal etkiye sahip olduğu ancak klinikte rutin olarak kullanılan irrigasyonlarla karşılaştırıldığında zayıf kaldığı sonucuna varılmıştır. Bu çalışma ağız ortamını simüle etmediği için gelecekteki çalışmalar daha etkili sonuçlar verebilir.
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UR  - https://doi.org/10.33483/jfpau.1601950
L1  - https://dergipark.org.tr/en/download/article-file/4442426
ER  -