TY - JOUR T1 - Effect of ImmuPlus on Growth and Inflammatory Response to Fruend's Complete Adjuvant in Common Carp, Cyprinus carpio (L.) TT - Effect of ImmuPlus on Growth and Inflammatory Response to Fruend's Complete Adjuvant in Common Carp, Cyprinus carpio (L.) AU - Priyadarshini, M. AU - Manissery, J.K. AU - Mohan, C. V. AU - Keshavanath, P. PY - 2012 DA - April JF - Turkish Journal of Fisheries and Aquatic Sciences PB - Trabzon Su Ürünleri Merkez Araştırma Enstitüsü WT - DergiPark SN - 1303-2712 VL - 12 IS - 2 LA - tr AB - The effect of 2 dosages (1.5 and 3.0%) of ImmuPlus, a polyherbal immunomodulator, was tested on growth and inflammatory response to Fruend's complete adjuvant (FCA) in common carp, Cyprinus carpio. The growth study was carried out for 120 days in nine 25 m2 outdoor cement tanks by feeding triplicate groups of 40 common carp fry (av. wt. 0.4 g ± 0.03) with a control (T0 without ImmuPlus) and two test diets (T1 and T2 with 1.5 and 3.0% ImmuPlus respectively). At the end of the growth experiment, 20 fish from each of these were used for evaluating the inflammatory response to FCA. The final weight gain of fish fed the test diets was significantly (P<0.05) higher, there being no difference between the two treatments. Specific growth rate of treated fish showed a significant increase (P<0.05) over that of the control fish. Supplementation of diet with ImmuPlus improved (P<0.05) survival of fish. Protein content of fish carcass was significantly (P<0.05) higher in the fish receiving the two test diets, while fat content was higher (P<0.05) only in fish from T2 treatment. Enhanced (P<0.05) protease and amylase activity was found in the treated fish. Even though there were no marked differences in the overall inflammatory response between the control and treated fish following FCA administration, recovery was faster in the latter, with stronger encapsulation of the adjuvant droplets. The results reflect the ability of Immuplus to promote growth and improve inflammatory response when administered through diet. KW - Cyprinus carpio KW - ImmuPlus KW - Carcass composition KW - Digestive enzymes KW - Fruend's adjuvant N2 - The effect of 2 dosages (1.5 and 3.0%) of ImmuPlus, a polyherbal immunomodulator, was tested on growth and inflammatory response to Fruend's complete adjuvant (FCA) in common carp, Cyprinus carpio. The growth study was carried out for 120 days in nine 25 m2 outdoor cement tanks by feeding triplicate groups of 40 common carp fry (av. wt. 0.4 g ± 0.03) with a control (T0 without ImmuPlus) and two test diets (T1 and T2 with 1.5 and 3.0% ImmuPlus respectively). At the end of the growth experiment, 20 fish from each of these were used for evaluating the inflammatory response to FCA. The final weight gain of fish fed the test diets was significantly (P<0.05) higher, there being no difference between the two treatments. Specific growth rate of treated fish showed a significant increase (P<0.05) over that of the control fish. Supplementation of diet with ImmuPlus improved (P<0.05) survival of fish. Protein content of fish carcass was significantly (P<0.05) higher in the fish receiving the two test diets, while fat content was higher (P<0.05) only in fish from T2 treatment. Enhanced (P<0.05) protease and amylase activity was found in the treated fish. Even though there were no marked differences in the overall inflammatory response between the control and treated fish following FCA administration, recovery was faster in the latter, with stronger encapsulation of the adjuvant droplets. The results reflect the ability of Immuplus to promote growth and improve inflammatory response when administered through diet. UR - https://dergipark.org.tr/en/pub/trjfas-ayrildi/issue//160261 L1 - https://dergipark.org.tr/en/download/article-file/141631 ER -