TY  - JOUR
T1  - Basic chromosome definitions and staining techniques
AU  - Küçük Yılmaz, Nihan
AU  - Börçek Kasurka, Ceren
AU  - Aydın, Yasemin Esin
AU  - Kaya, Aleyna
PY  - 2025
DA  - August
Y2  - 2025
JF  - Middle Black Sea Journal of Health Science
JO  - Mid Blac Sea J Health Sci
PB  - Ordu University
WT  - DergiPark
SN  - 2149-7796
SP  - 268
EP  - 283
VL  - 11
IS  - 3
LA  - en
AB  - The essential molecules that preserve genetic information, control expression, and guarantee accurate and complete transfer are chromosomes. Any disruption in any of these stages will also be reflected in the organism. Therefore, understanding the "normal" of chromosomes—such as normal packing or normal separation—is crucial for identifying the root causes of disorders. From a health sciences perspective, identifying the relationship between chromosomes and disorders is the first step toward diagnoses, advanced research for numerous diseases, and even treatment recommendations. While more complicated, quick, and accurate methods have emerged due to methodological developments, traditional chromosomal approaches continue to be the most important and innovative in many labs.In the context of all mentioned above, this review gives a general overview of the packaging and classification of eukaryotic chromosomes as well as the grouping of human chromosomes. It also presents the basic concepts underlying the G, C, Q, R, and T banding and NOR staining techniques and discusses their consequences for human chromosomes.
KW  - chromosome structure
KW  - banding techniques
KW  - chromosome classification
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UR  - https://dergipark.org.tr/en/pub/mbsjohs/issue//1602807
L1  - https://dergipark.org.tr/en/download/article-file/4446287
ER  -