TY - JOUR T1 - Evaluation of the efficiency of TENS therapy to the regeneration in N. ischiadicus injured rats TT - Evaluation of the efficiency of TENS therapy to the regeneration in N. ischiadicus injured rats AU - Eravcı Yalın, Ebru AU - Devecioğlu, Yalçın PY - 2024 DA - December Y2 - 2024 JF - Journal of Istanbul Veterinary Sciences JO - J Ist Vet Sci PB - The Chamber of Veterinary Surgeons, Istanbul WT - DergiPark SN - 2602-3490 SP - 335 EP - 342 VL - 8 IS - 3 LA - en AB - Transcutaneous electrical nerve stimulation (TENS) is one of the electrotherapy methods, used for physical therapy, to relieve neuropathic pain in the nervous system lesion. However, the effect on peripheral nerve regeneration has been unknown. This work aims to examine peripheral nervous system diseases in which fullness is preserved, the efficiency of TENS to hasten healing, and the suitability of magnetic resonance imaging to diagnose peripheral nervous system diseases. Also, electrophysiologic findings of functional nerve recuperation will be considered after comparing with histopathologic and magnetic resonance imaging. 72 Sprague Dawley rats were randomly assigned to four groups. Group 1; normal without crush lesion, Group 2; control group with crush lesion, Group 3; stimulated group on lesion area, Group 4; stimulated group on gastrocnemius muscle. The animals were sacrificed post-operatively 21. day and 45. day after the electrophysiological, assessment and walking trace analysis, magnetic resonance imaging and nerve samples were obtained for histologic analysis. According to this study, low-frequency TENS leads to delayed regeneration after a crush lesion of the sciatic nerve in rats. KW - TENS KW - rat KW - nerve regeneration KW - EMG KW - electrophysiology N2 - Transcutaneous electrical nerve stimulation (TENS) is one of the electrotherapy methods, used for physical therapy, to relieve neuropathic pain in the nervous system lesion. However, the effect on peripheral nerve regeneration has been unknown. This work aims to examine peripheral nervous system diseases in which fullness is preserved, the efficiency of TENS to hasten healing, and the suitability of magnetic resonance imaging to diagnose peripheral nervous system diseases. Also, electrophysiologic findings of functional nerve recuperation will be considered after comparing with histopathologic and magnetic resonance imaging. 72 Sprague Dawley rats were randomly assigned to four groups. Group 1; normal without crush lesion, Group 2; control group with crush lesion, Group 3; stimulated group on lesion area, Group 4; stimulated group on gastrocnemius muscle. The animals were sacrificed post-operatively 21. day and 45. day after the electrophysiological, assessment and walking trace analysis, magnetic resonance imaging and nerve samples were obtained for histologic analysis. 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UR - https://dergipark.org.tr/en/pub/http-www-jivs-net/issue//1602816 L1 - https://dergipark.org.tr/en/download/article-file/4446326 ER -