TY  - JOUR
T1  - Comparison of testicular elasticity with histogram analysis of testicular echogenicity
TT  - Testis elastikiyetinin testis ekojenitesinin histogram analizi ile karşılaştırılması
AU  - Güngör, Gülay
AU  - Doğan, Adil
AU  - Ciner, Mahmut
AU  - Baykara, Murat
PY  - 2025
DA  - March
Y2  - 2025
DO  - 10.16899/jcm.1611569
JF  - Journal of Contemporary Medicine
JO  - J Contemp Med
PB  - Rabia YILMAZ
WT  - DergiPark
SN  - 2667-7180
SP  - 58
EP  - 62
VL  - 15
IS  - 2
LA  - en
AB  - ABSTRACTAim: This study aims to evaluate the relationship between testicular tissue elasticity and ultrasound (US) histogram analysis obtained from testicular echo signals. The goal is to explore whether quantitative texture analysis can complement traditional US findings.Materials and Methods: 46 patients with 92 testis were examined using B-mode ultrasound and strain elastography (SE). A transverse US image was analyzed for each testis to extract histogram parameters such as mean, standard deviation, skewness, kurtosis, and entropy. SE was used to measure testicular elasticity.Results: Histogram analysis showed a significant correlation between age and homogenization of testicular tissue (r = 0.444; p
KW  - Histogram analysis
KW  - Male infertility
KW  - Testis
KW  - Ultrasound elastography
N2  - ÖZETAmaç: Bu çalışmanın amacı testis dokusu elastikiyeti ile testis eko sinyallerinden elde edilen ultrason (US) histogram analizi arasındaki ilişkiyi değerlendirmektir. Amaç, kantitatif doku analizinin geleneksel US bulgularını tamamlayıp tamamlayamayacağını araştırmaktır.Gereç ve Yöntem: 92 testisi olan 46 hasta B-mod ultrason ve gerinim elastografisi (SE) kullanılarak incelendi. Her testis için ortalama, standart sapma, çarpıklık, basıklık ve entropi gibi histogram parametrelerini çıkarmak için transvers US görüntüsü analiz edildi. SE, testis elastikiyetini ölçmek için kullanıldı.Bulgular: Histogram analizi yaş ile testis dokusunun homojenizasyonu arasında önemli bir korelasyon gösterdi (r = 0,444; p
CR  - 1.	Trottmann M, Marcon J, D'Anastasi M, et al. Shear-wave elastography of the testis in the healthy man- determination of standard values. Clin Hemorheol Microcirc 2016;62(3):273-81.
CR  - 2.	Nieschlag E, Behre HM. Approaches to hormonal male contraception. In: Nieschlag E, Behre HM, Nieschlag S, editors. Andrology: male reproductive health and dysfunction, 3rd edn. Springer, Heidelber; 2010. pp 577–587
CR  - 3.	Lotti F, Maggi M. Ultrasound of the male genital tract in relation to male reproductive health. Hum Reprod Update 2015;21(1):56-83.
CR  - 4.	Bernardo S, Konstantatou E, Huang DY, et al. Multiparametric sonographic imaging of a capillary hemangioma of the testis: appearances on grayscale, color Doppler, contrast-enhanced ultrasound and strain elastography. J Ultrasound 2015;19(1):35-9.
CR  - 5.	Rocher L, Criton A, Gennisson JL, et al. Testicular Shear Wave Elastography in Normal and Infertile Men: A Prospective Study on 601 Patients. Ultrasound Med Biol 2017;43(4):782-789.
CR  - 6.	Oglat AA, Abukhalil T. Ultrasound Elastography: Methods, Clinical Applications, and Limitations: A Review Article. Applied Sciences 2024;14(10):4308.
CR  - 7.	Schurich M, Aigner F, Frauscher F, Pallwein L. The role of ultrasound in assessment of male fertility. Eur J Obstet Gynecol Reprod Biol 2009;144 Suppl 1: S192-8.
CR  - 8.	Sarvazyan A, Hall TJ, Urban MW, Fatemi M, Aglyamov SR, Garra BS. An overview of elastography-an emerging branch of medical imaging. Curr Med Imaging Rev 2011;7(4):255-82.
CR  - 9.	Goddi A, Sacchi A, Magistretti G, Almolla J, Salvadore M. Real-time tissue elastography for testicular lesion assessment. Eur Radiol 2012;22(4):721-30. 
10.	Lai DK, Cheng ES, Mao YJ, et al. Sonoelastography for Testicular Tumor Identification: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy. Cancers (Basel) 2023;15(15):3770.
CR  - 11.	Gillies RJ, Kinahan PE, Hricak H. Radiomics: Images Are More than Pictures, They Are Data. Radiology 2016;278(2):563-77.
CR  - 12.	Fanni SC, Febi M, Colligiani L, et al. A first look into radiomics application in testicular imaging: A systematic review. Front Radiol 2023; 3:1141499.
CR  - 13.	De Santi B, Spaggiari G, Granata AR, et al. From subjective to objective: A pilot study on testicular radiomics analysis as a measure of gonadal function. Andrology 2022;10(3):505-17.
CR  - 14.	Cui XW, Li KN, Yi AJ, et al. Ultrasound elastography. Endosc Ultrasound 2022;11(4):252-74.
CR  - 15.	Urhuț MC, Săndulescu LD, Ciocâlteu A, Cazacu SM, Dănoiu S. The Clinical Value of Multimodal Ultrasound for the Differential Diagnosis of Hepatocellular Carcinoma from Other Liver Tumors in Relation to Histopathology. Diagnostics (Basel) 2023;13(20):3288.
CR  - 16.	DeJohn CR, Grant SR, Seshadri M. Application of Machine Learning Methods to Improve the Performance of Ultrasound in Head and Neck Oncology: A Literature Review. Cancers (Basel) 2022;14(3):665.
CR  - 17.	Lotti F, Studniarek M, Balasa C, et al.  The role of the radiologist in the evaluation of male infertility: recommendations of the European Society of Urogenital Radiology-Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for scrotal imaging.  Eur Radiol. 2025;35(2):752-66.
CR  - 18.	Spaggiari G, M Granata AR, Santi D. Testicular ultrasound inhomogeneity is an informative parameter for fertility evaluation. Asian J Androl 2020;22(3):302-308.
CR  - 19.	Lotti F, Frizza F, Balercia G, et al. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: An overview on male genital tract ultrasound reference ranges. Andrology 2022;10 Suppl 2(Suppl 2):118-32.
CR  - 20.	Pietsch FL, Haag F, Ayx I, et al. Textural heterogeneity of liver lesions in CT imaging-comparison of colorectal and pancreatic metastases. Abdom Radiol (NY) 2024;49(12):4295-306.
CR  - 21.	Yoon J, Lee E, Kang SW, Han K, Park VY, Kwak JY. Implications of US radiomics signature for predicting malignancy in thyroid nodules with indeterminate cytology. Eur Radiol 2021;31(7):5059-67.
CR  - 22.	Satoh Y, Hirata K, Tamada D, Funayama S, Onishi H. Texture Analysis in the Diagnosis of Primary Breast Cancer: Comparison of High-Resolution Dedicated Breast Positron Emission Tomography (dbPET) and Whole-Body PET/CT. Front Med (Lausanne) 2020;7:603303.
CR  - 23.	Abbasian Ardakani A, Sattar AR, Abolghasemi J, Mohammadi A. Correlation between Kidney Function and Sonographic Texture Features after Allograft Transplantation with Corresponding to Serum Creatinine: A Long-Term Follow-Up Study. J Biomed Phys Eng 2020;10(6):713-26.
CR  - 24.	Huang X, Chen M, Liu P, Du Y. Texture Feature-Based Classification on Transrectal Ultrasound Image for Prostatic Cancer Detection. Comput Math Methods Med 2020;(6);2020: 7359375.
CR  - 25.	Ghayda RA, Cannarella R, Calogero AE, et al. Artificial Intelligence in Andrology: From Semen Analysis to Image Diagnostics. World J Mens Health 2024;42(1):39-61.
UR  - https://doi.org/10.16899/jcm.1611569
L1  - https://dergipark.org.tr/en/download/article-file/4485170
ER  -