TY  - JOUR
T1  - Transdermal Drug Delivery in Oncology Charting the Road Ahead
AU  - Rane, Bhushan
AU  - Gawade, Sanskruti
PY  - 2025
DA  - September
Y2  - 2025
DO  - 10.52794/hujpharm.1611956
JF  - Hacettepe University Journal of the Faculty of Pharmacy
JO  - HUJPHARM
PB  - Hacettepe University
WT  - DergiPark
SN  - 2458-8806
SP  - 286
EP  - 299
VL  - 45
IS  - 3
LA  - en
AB  - Transdermal drug administration is a method of administering medication through the skin that is non-intrusive, offering an innovative and hopeful alternative to traditional oral and injection methods. Advancements in skin penetration technology have enabled the transdermal administration of various anticancer medications, including lipophilic or hydrophilic compounds, offering a new approach to cancer treatment. Research has explored innovative platforms for cancer treatment, such as erythrocytes, vesicles, and exosomes. The most efficient approach is the transdermal drug delivery system. This review investigates various transdermal delivery techniques beyond the pharmaceutical sector in relation to cancer treatment. Techniques include iontophoresis, electroporation, sonophoresis, microneedles, transdermal patches, or vesicular systems like liposomes, niosomes, transferosomes, ethosomes, transethosomes, nanoparticles, carbon nanotubes, quantum dots, as well as nanofibers, which have been used to improve transdermal distribution and their use in cancer treatment. Additionally, a roadmap is presented to guide development strategies, highlighting the multiple applications of transdermal drug administration systems for cancer therapy.
KW  - Transdermal drug delivery
KW  - Skin cancer
KW  - Breast cancer
KW  - Nanoparticles
KW  - Vesicular system.
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UR  - https://doi.org/10.52794/hujpharm.1611956
L1  - https://dergipark.org.tr/en/download/article-file/4486857
ER  -