TY  - JOUR
T1  - Synthesis, Characterization, Antimicrobial Activities and Molecular Docking Studies of Nanoparticles from Polygonum cognatum, Mentha pulegium and Tragopogon reticulatus
TT  - Polygonum cognatum, Mentha pulegium ve Tragopogon reticulatus'tan Elde Edilen Nanopartiküllerin Sentezi, Karakterizasyonu, Antimikrobiyal Aktiviteleri ve Moleküler Yerleştirme Çalışmaları
AU  - Yiğit, Aybek
AU  - Aslan, Saniye
AU  - Başar, Yunus
PY  - 2025
DA  - August
Y2  - 2025
DO  - 10.53433/yyufbed.1621096
JF  - Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi
JO  - YYUFBED
PB  - Van Yuzuncu Yıl University
WT  - DergiPark
SN  - 1300-5413
SP  - 537
EP  - 554
VL  - 30
IS  - 2
LA  - en
AB  - Nanotechnology and its applications are increasing day by day in the food industry, medicine, pharmacy, cosmetics and industrial sectors as technology develops. However, research into their impact on human health and nature continues. In this study, Ag, Cu and Fe nanoparticles (NPs) were obtained from the plants Polygonum cognatum, Mentha pulegium, and Tragopogon reticulatus by methanol extracts and green synthesis. The characteristic properties of these synthesized particles were tested by FE-SEM, FESEM-EDX, UV-Vis, FT-IR and HPLC. The antimicrobial activities of the extracts and NPs obtained against the microorganisms Staphylococcus aureus, Enterococcus faecalis and Pseudomonas aeruginosa were tested using the disk diffusion method. Also, the inhibitory properties of the molecules and NP complexes identified in HPLC analysis against the enzyme topoisomerase IV were theoretically calculated by molecular docking.  In HPLC analysis, chlorogenic acid (P. cognatum and T. reticulatus) and chrysin (M. pulegium) were detected in the highest amounts.  In studies on antibacterial activity, all  NPs  obtained from P. cognatum, M. pulegium and T. reticulatus showed activity against S. aureus. According to the molecular docking result, chlorogenic acid-AgNP and chrysin-CuNP had higher MolDock values.  As a result, the NPs and extracts made from these plants have use in medicine, food, and cosmetics.
KW  - Antibacterial
KW  - Mentha pulegium
KW  - Molecular docking
KW  - Nanoparticle
KW  - Polygonum cognatum
KW  - Tragopogon reticulatus
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UR  - https://doi.org/10.53433/yyufbed.1621096
L1  - https://dergipark.org.tr/en/download/article-file/4526036
ER  -