@article{article_1624935, title={Antioxidant, antiradical properties, vitamin and trace element status of Artemisia spicigera C. Koch distributed in the Türkiye flora}, journal={Trakya University Journal of Natural Sciences}, volume={26}, pages={118–126}, year={2025}, author={Yıldız, Damla and Bakır, Ahmet and Ekin, Suat and Özgökçe, Fevzi}, keywords={Artemisia spicigera, reactive oxygen species, metal, α-tocopherol, phylloquinone}, abstract={It is known that the active substances present in plants contribute to many biochemical processes and provide the balance of organisms. This study aims to determine the antioxidant and antiradical properties of the methanol extract of Artemisia spicigera (A. spicigera) C. Koch leaves and to measure the levels of trace elements and vitamins E and K. Trace element analyses were performed by the Inductively Coupled Plasma - Optical Emission Spectroscop dry ashing and vitamin analyses were performed by the High Performance Liquid Chromatography method. Vitamin C, total phenol and flavonoid contencts, antioxidant capacity, DPPH•, ABTS•+, O2•-, H2O2 and OH• values were determined spectrophotometrically. Total phenolic and flavonoid contents and antioxidant capacity were determined as 18.45 ± 0.39 mgGA/g, 26.29 ± 1.64 mgQE/g and 44.08 ± 2.91 mMAA/g, respectively. Mn, Zn, Cu, α-tocopherol, phylloquinone and ascorbic acid levels were found as 287.32 ± 0.57, 104.36 ± 2.12, 37.40 ± 0.10, 10.28 ± 0.75, 0.149 ± 0.047 μmol/kg and 217.36 ± 29.20 mg/100g, respectively. In vitro antioxidant properties determined by DPPH•, ABTS•+, H2O2 and OH• assays showed maximum inhibitory with respective IC50 values of 61.83 ± 0.68, 71.74 ± 0.79, 34.25 ± 0.74 and 77.91 ± 0.88 μg/mL. The IC50 values of these assays showed promising antioxidant power. The results obtained in this study showed that the plant leaves migth be a potential candidate for in vivo studies to be evaluated in the future. A. spicigera can be also used as a potential supplement or in the pharmaceutical industries as a source of natural antioxidants.}, number={2}, publisher={Trakya University}, organization={Van Yüzüncü Yıl University Scientific Research Projects Coordination Unit}