TY - JOUR T1 - A Rare Case of Bladder Tumor: Squamous Cell Papilloma TT - Nadir bir mesane tümörü vakası: Skuamöz hücreli papilloma AU - Akça, Görkem AU - Uzun, Hakkı AU - Güçer, Hasan AU - Dil, Eyüp AU - Yazar, Selim AU - Orman, Erdem PY - 2025 DA - June Y2 - 2025 DO - 10.33719/nju1630050 JF - The New Journal of Urology JO - New J Urol PB - Ali İhsan TAŞÇI WT - DergiPark SN - 3023-6940 SP - 117 EP - 120 VL - 20 IS - 2 LA - en AB - Squamous cell papilloma of the bladder is an exceedingly rare benign lesion. It is often identified incidentally during imaging studies performed for unrelated reasons and may mimic urothelial carcinoma of the bladder. The definitive diagnosis of this lesion, which can present with varying clinical symptoms, is established through pathological examination. Here, we report a case of squamous cell papilloma in a 56-year-old asymptomatic male patient. The patient underwent cystoscopy after a suspicious lesion was observed on full-abdominal CT imaging, raising concern for a bladder tumor. During cystoscopy, transurethral resection was performed on calcified exophytic lesions observed in the bladder, achieving complete resection of all lesions. Histopathological analysis revealed the lesion to be a squamous cell papilloma, and the patient was placed under follow-up. The etiology and clinical significance of these lesions, which are rarely reported in the literature, remain unclear. In this article, we summarize the case of squamous cell papilloma of the bladder while reviewing the relevant literature. We believe that this report contributes to the literature by emphasizing the importance of accurate pathological evaluation for urologists and preventing overly aggressive treatments for patients. KW - Papilloma KW - squamous KW - bladder N2 - Mesanenin skuamöz hücreli papilloması oldukça nadir görülen benign bir lezyondur. Çoğunlukla herhangi bir nedenle yapılan görüntüleme tetkiğinde insidental olarak saptanır ve mesanenin ürotelyal karsinomunu taklit eder. Farklı klinik semptomlar gösterebilen bu lezyonun kesin tanısı patolojik inceleme neticesinde konulur. Biz burada asemptomatik olan 56 yaşındaki erkek hastada saptadığımız skuamöz hücreli papilloma vakasını sunuyoruz. Hastaya tüm abdomen BT görüntülemesinde mesane tümörü açısından şüpheli lezyon izlenmesi üzerine sistoskopi yapıldı. Sistoskopide mesanede izlenen üzeri kalsifiye ekzofitik lezyonlara transüretral rezeksiyon uygulanarak tüm lezyonlar komplet rezeke edildi. Histopatolojik inceleme neticesinde lezyonun skuamöz hücreli papilloma olduğu ortaya çıktı ve hasta takibe alındı. Literatürde az sayıda bildirilen bu lezyonların etyolojisi ve klinik önemi belirsizdir. Biz bu yazıda mesanenin skuamöz hücreli papilloma vakasını literatürü gözden geçirerek özetledik. Bu yazının ürolog için doğru bir patolojik incelemenin öneminin vurgulanması ve hasta için de agresif tedavilerin önüne geçilmesi açısından literatüre katkı sağlayacağını düşünmekteyiz. CR - 1. Busch C, Johansson SL. Urothelial papilloma. In: Eble JN, Sauter G, Epstein JI, Sesterhenn IA, editors. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. 3rd edition. Lyon, France: IARC Press; 2004. p. p. 113.  CR - 2. Brown JT, Narayan VM, Joshi SS, et al. Challenges and opportunities in the management of non-urothelial bladder cancers. Cancer Treat Res Commun. 2023;34:100663. https://doi.org/10.1016/j.ctarc.2022.100663 CR - 3. Guo CC, Fine SW, Epstein JI. Noninvasive squamous lesions in the urinary bladder: a clinicopathologic analysis of 29 cases. Am J Surg Pathol. 2006;30(7):883-891. https://doi.org/10.1097/01.pas.0000213283.20166.5a CR - 4. Sengupta S, Basu S, Ghosh K, et al. Urethral squamous papilloma with multiple bladder diverticulum: A case report and literature review. Urol Case Rep. 2021;37:101638. Published 2021 Mar 13. https://doi.org/10.1016/j.eucr.2021.101638 CR - 5. Miliaras D, Vakalopoulos I, Anagnostou E. Squamous cell papilloma of the urinary bladder endoscopically mimicking cancer. Case Rep Pathol. 2013;2013:486312. https://doi.org/10.1155/2013/486312 CR - 6. Takei K, Otsuki Y. Hinyokika Kiyo. 2020;66(11):403-406. https://doi.org/10.14989/ActaUrolJap_66_11_403 CR - 7. Mohamed A, Khalil IA, Aldeeb M, et al. Squamous cell papilloma a rare urinary bladder tumor, case report and operative video. Urol Case Rep. 2022;43:102074. https://doi.org/10.1016/j.eucr.2022.102074 CR - 8. Cheng L, Leibovich BC, Cheville JC, et al. Squamous papilloma of the urinary tract is unrelated to condyloma acuminata. Cancer. 2000;88(7):1679-1686. https://doi.org/10.1002/(sici)1097-0142(20000401)88:7 <1679::aid-cncr23>3.0.co;2-k CR - 9. Jaju PP, Suvarna PV, Desai RS. Squamous papilloma: case report and review of literature. Int J Oral Sci. 2010;2(4):222-225. https://doi.org/10.4248/IJOS10065 UR - https://doi.org/10.33719/nju1630050 L1 - https://dergipark.org.tr/en/download/article-file/4565771 ER -