@article{article_1635603, title={Impact of Mydriatic Drops and Pain on Systemic Responses During Retinopathy of Prematurity Screening}, journal={Online Turkish Journal of Health Sciences}, volume={10}, pages={131–138}, year={2025}, author={Bilgin, Gülay and Tekcan, Demet and Erdoğan, Mustafa Gürkan and Güven, Şirin}, keywords={Mydriatic drops, neonatal intensive care units, neonatal pain, preterm infants, retinopathy of prematurity}, abstract={ABSTRACT
Objective: Retinopathy of Prematurity (ROP) stands as a critical challenge faced by neonatal intensive care units (NICUs). The ROP examination usually begins when the patients are in the NICU, then are followed up in policlinics. Thus, side effects of examination procedure may occur in the home, frightening members of the family. So, our objective to investigate the impact of neonatal pain on systemic and procedural side effects of ROP examinations and mydriatic drops to improve screening safety. Materials And Methods: The study planned as a prospective descriptive investigation, was conducted with 70 preterm infants admitted to the NICU between August and November 2012. Patients monitored during examination and 48 hours after than for vital signs and recording any side effects. Neonatal İnfant Pain Scale was performed all patients. For statistical analysis SPSS 15 was used.
Results: Adverse effects were absent in 41.4% of the infants. Flushing was noted in 22.9%, gastric residuals in 10%, vomiting in 8.6%, and a combination of flushing with apnea and gastric residuals in 2.9% of the infants. The pain group was associated with temporary increases in heart rate and body temperature, which were primarily noticeable in the first hour after the examination. There was no relationship between pain and blood pressure, oxygen saturation level, or respiratory rate.
Conclusions: A comprehensive understanding of the adverse effects associated with mydriatic drops and the examination procedure is essential. During ROP screening, infants should be carefully monitored in standardized clinical settings, with appropriate pain management strategies in place, and caregivers should receive thorough discharge education.
Keywords: Infant, Premature; Mydriatics; Pain; Retinopathy of Prematurity; Vital SignsObjective: Retinopathy of Prematurity (ROP) presents a significant challenge for neonatal intensive care units (NICUs). Therefore, the study aims to investigate the impact of neonatal pain on the systemic and procedural side effects of ROP examinations and mydriatic drops, with the aim of enhancing screening safety.
Materials And Methods: This study, designed as a prospective descriptive investigation, included 70 preterm infants admitted to the NICU between August and November 2012. Patients were monitored during the examination and for 48 hours afterwards, focusing on vital signs and any side effects. The Neonatal Infant Pain Scale was applied to all patients. Statistical analysis was conducted using SPSS version 15. Results: Adverse effects were absent in 41.4% of the infants. Flushing was observed in 22.9%, gastric residuals were noted in 10%, vomiting occurred in 8.6%, and a combination of flushing, apnea, and gastric residuals was seen in 2.9% of the infants. The pain group exhibited temporary increases in heart rate and body temperature, most notably within the first hour after the examination. There were no significant relationships between pain and blood pressure, oxygen saturation levels, or respiratory rates (p>0.05). Conclusions: A comprehensive understanding of the adverse effects associated with mydriatic drops and the examination procedure is essential. During ROP screenings, infants should be closely monitored in standardized clinical settings, appropriate pain management strategies should be implemented, and caregivers must receive thorough education upon discharge.}, number={2}, publisher={Oğuz KARABAY}, organization={There is no conflict of interest.}