TY - JOUR T1 - Catheter-Related Bloodstream Infection Caused by Kingella Denitrificans: A Case Report TT - Kingella Denitrificans’ın Neden Olduğu Kateterle İlişkili Kan Dolaşımı Enfeksiyonu: Bir Vaka Raporu AU - Öz, Murtaza AU - Aldemir, Özlem PY - 2025 DA - September Y2 - 2025 DO - 10.35440/hutfd.1649413 JF - Harran Üniversitesi Tıp Fakültesi Dergisi PB - Harran University WT - DergiPark SN - 1304-9623 SP - 618 EP - 620 VL - 22 IS - 3 LA - en AB - Kingella denitrificans is a gram-negative coccobacillus that, although rare, can be a human pathogen. Infections such as endocarditis and peritonitis have been reported in the literature. Here, we report a previously undocumented catheter-related bloodstream infection caused by Kingella denitrificans. Although an antibiogram was not performed for the microorganism, clinical and laboratory findings improved with intravenous meropenem treatment and the re-moval of the infected permanent tunneled subclavian catheter. KW - Kingella denitrificans KW - meropenem KW - catheter-related infection KW - fever KW - bacteria N2 - Kingella denitrificans, nadir görülmesine rağmen insanlarda patojen olabilen gram-negatif bir kokobasildir. Literatürde endokardit ve peritonit gibi enfeksiyonlara dair vakalar bildirilmiştir. Bu çalışmada, daha önce belgelenmemiş Kingella denitrificans kaynaklı kateterle ilişkili bir kan dolaşımı enfeksiyonunu sunuyoruz. Mikroorganizma için bir antibiyogram testi yapılmamış olmasına rağmen, intravenöz meropenem tedavisi ve enfekte olmuş kalıcı tünelli subklavyen kateterin çıkarılmasıyla klinik ve laboratuvar bulgularında iyileşme sağlanmıştır. CR - 1. Murphy TF. Moraxella catarrhalis, Kingella, and Other Gram-Negative Cocci. In: Bennett JE, Dolin R, Blaser MJ (eds). Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Elsevier: Amsterdam, The Netherlands; 2019, pp: 2628-35 CR - 2. Yagupsky P, Greenberg D. Kingella species. In: Sarah S. Long (ed) Principles and Practice of Pediatric Infectious Diseases. Philadelphia Elsevier Inc 2012, p: 919-922. CR - 3. Lehenaff R, Tamashiro R, Nascimento MM, Lee K, Jenkins R, Whitlock J, et al. Subgingival microbiome of deep and shal-low periodontal sites in patients with rheumatoid arthritis: a pilot study. BMC Oral Health. 2021;21(1):248. https://doi.org/10.17026/dans-zsb-wg2f CR - 4. Weir S, Lee LW, Marrs CF. Type-4 pili of Kingella denitrifi-cans. Gene. 1997;192(1):171-6. https://doi.org/10.1016/S0378-1119(96)00828-1 CR - 5. Kocyigit I, Öztürk F, Kargi S, Uzun I, Unal A, Tokgoz B. Perito-neal Dialysis-Related Peritonitis Due toKingella Denitrificans: The First Case Report. Perit Dial Int. 2014;34(7):819-20. https://doi.org/10.3747/pdi.2013.00149 CR - 6. Khan JA, Sharp S, Mann KR, Brewer J. Case Report: Kingella denitrificans Prosthetic Endocarditis. Am J Med Sci. 1986; 291(3):187-9. https://doi.org/10.1097/00000441-198603000-00009 CR - 7. Maccato M, McLean W, Riddle G, Faro S. Isolation of Kingella denitrificans from amniotic fluid in a woman with chorioam-nionitis. A case report. J Reprod Med. 1991; 36(9):685-7. CR - 8. Knapp JS, Johnson SR, Zenilman JM, Roberts MC, Morse SA. High-level tetracycline resistance resulting from TetM in strains of Neisseria spp., Kingella denitrificans, and Eikenella corrodens. Antimicrob Agents Chemother. 1988; 32(5):765-7. https://doi.org/10.1128/aac.32.5.765 CR - 9. Matuschek E, Åhman J, Kahlmeter G, Yagupsky P. Antimicro-bial susceptibility testing of Kingella kingae with broth mic-rodilution and disk diffusion using EUCAST recommended media. Clinical Microbiology and Infection. 2018; 24(4):396-401. https://doi.org/10.1016/j.cmi.2017.07.019 CR - 10. Baang JH, Inagaki K, Nagel J, Ramani K, Stillwell TL, Mack M, et al. Inpatient Diagnosis and Treatment of Catheter-Related Bloodstream Infection [Internet]. Ann Arbor (MI): Michigan Medicine University of Michigan; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK589895/ UR - https://doi.org/10.35440/hutfd.1649413 L1 - https://dergipark.org.tr/en/download/article-file/4652301 ER -