TY - JOUR T1 - Effect of Monitoring with Bispectral Index (BIS) on Depth of Anesthesia and Recovery in Sevoflurane and Isoflurane Anesthesia AU - Sazak, Hilal AU - Uluçinar, Ergül AU - Tunç, Mehtap AU - Alagöz, Ali AU - İbiş, Fatma AU - Ulus, Fatma AU - Karslıoğlu, Onur PY - 2025 DA - May Y2 - 2025 JF - Sanatorium Medical Journal JO - Sanatorium Med J PB - T.C. Sağlık Bakanlığı Ankara Atatürk Sanatoryum Eğitim ve Araştırma Hastanesi WT - DergiPark SN - 3062-3944 SP - 37 EP - 44 VL - 1 IS - 1 LA - en AB - AimWe aimed to evaluate the effect of bispectral index (BIS) monitoring on anesthesia depth and recovery in patients undergoing thoracic surgery under sevoflurane and isoflurane anesthesia.Material MethodAfter the hospital ethics committee approval, sixty ASA class I-II and the ages between 20-60 years elective thoracotomy patients were randomly divided into four groups; Group 1: Sevoflurane-Control, Group 2: Sevoflurane-BIS, Group 3: Isoflurane-Control, and Group 4: Isoflurane-BIS. Invasive arterial pressure and BIS monitorization were performed with standard anesthesia guidelines. After midazolam premedication, standard anesthesia induction was performed. However, in the groups where BIS monitorization was performed, sevoflurane and isoflurane were adjusted to provide 45-55 BIS values during the operation and 60-75 in the last 15 minutes of the surgery. The initial parameters, BIS, end-tidal carbon dioxide (EtCO2), fractioned inspired volatile anesthetic concentration (FiVAC) end-tidal volatile anesthetic, minimum alveolar concentration (MAC) values, total additional fentanyl and vecuronium bromide doses, time to respond to a verbal stimulus after anesthetic gas was interrupted, durations of extubation, orientation, and recovery of the patients were recorded. In addition, they were asked whether they remembered anything about the operation 24 hours later postoperatively.ResultsNo significant difference was found between intraoperative hemodynamic data, FİVAC, ETVAC, MAC values, and BIS values between the groups (p > 0.05). No difference was found from the point of view of time for response to verbal stimulus, extubation, orientation, and recovery between the control and BIS groups, and none of the subjects remembered anything about the operation 24 hours later postoperatively.ConclusionOur study showed that adequate depth of anesthesia was achieved in both the control and BIS groups BIS monitoring was not found to improve quality of awakening and recovery. It was thought that BIS monitoring might be useful for those with less clinical experience rather than for experienced anesthesiologists. KW - Sevoflurane KW - Isoflurane KW - Bispectral Index (BIS) KW - Recovery CR - 1. 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