TY  - JOUR
T1  - Serotonin Syndrome After Alcohol and Methamphetamine Ingestion in a Patient on Escitalopram: Case Presentation
AU  - Saral Öztürk, Zeynep
AU  - Özen Olcay, Handan
AU  - Çevik, Yunsur
PY  - 2025
DA  - September
Y2  - 2025
JF  - Sanatorium Medical Journal
JO  - Sanatorium Med J
PB  - T.C. Sağlık Bakanlığı Ankara Atatürk Sanatoryum Eğitim ve Araştırma Hastanesi
WT  - DergiPark
SN  - 3062-3944
SP  - 100
EP  - 102
VL  - 1
IS  - 2
LA  - en
AB  - Background: Serotonin syndrome is a rare but potentially life-threatening condition characterized by excessive serotonergic activity. This report describes a case of SS in a patient undergoing long-term escitalopram therapy who developed symptoms following the ingestion of methamphetamine and alcohol.Case Presentation: A 42-year-old male on escitalopram presented with agitation, confusion, myoclonic movements, and a localized rash after methamphetamine and alcohol ingestion. Vital signs showed mild hypertension, low-grade fever, and hypoxemia; labs and ECG were normal. He improved rapidly with fluids, diazepam, and paracetamol, and was discharged after observation.Conclusion: Clinical presentation included agitation, spontaneous clonus, and an unusual bullous skin lesion. Prompt supportive treatment led to symptom resolution, and the patient was discharged within six hours. This case underscores the importance of clinical vigilance for SS, particularly in patients with concurrent substance use and stable antidepressant therapy.
KW  - serotonin syndrome
KW  - escitalopram
KW  - alcohol
KW  - methamphetamine
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UR  - https://dergipark.org.tr/en/pub/sanatoriummedj/issue//1667106
L1  - https://dergipark.org.tr/en/download/article-file/4732512
ER  -