TY - JOUR T1 - The value of the second trimester glucose-to-lymphocyte ratio in predicting fetal loss at late preterm and term pregnancies AU - Özkavak, Osman Onur AU - Sahin, Dilek PY - 2025 DA - March Y2 - 2025 DO - 10.5505/achmedj.2025.69875 JF - ACH Medical Journal JO - ACH Med J PB - Ankara Şehir Hastanesi WT - DergiPark SN - 2822-5872 SP - 22 EP - 26 VL - 4 IS - 1 LA - en AB - Introductıon: This study aimed to determine whether the second-trimester glucose-to-lymphocyte ratio (GLR) can predict intrauterine fetal demise (IUFD) at late preterm and term gestations.Methods: A retrospective cross-sectional design was employed. Pregnant women aged 18–45 who delivered at our tertiary hospital between January 2023 and December 2024 were screened. Those diagnosed with IUFD at or beyond 34 weeks of gestation comprised the case group, while two healthy pregnant women of similar age and body mass index for each case served as the control group. Laboratory parameters from the 20th–24th weeks, including hemoglobin, white blood cell (WBC) count, neutrophil count, lymphocyte count, random blood glucose, and GLR, were analyzed.Results: Data from 105 patients (35 IUFD, 70 controls) were included. The IUFD group had significantly lower WBC, neutrophil, and lymphocyte counts but higher glucose and GLR than controls (p KW - Intrauterine fetal demise KW - Glucose-to-lymphocyteratio KW - Inflammatory marker CR - 1. Barfield, W. D. & COMMITTEE ON FETUS AND NEWBORN. (2016). Standard Terminology for Fetal, Infant, and Perinatal Deaths. Pediatrics, 137(5), e20160551. https://doi.org/10.1542/peds.2016-0551 CR - 2. Dave, A., Patidar, R., Goyal, S., & Dave, A. (2016). Intrauterine fetal demise-a tragic event: A study of its epidemiology, causes and methods of induction. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 5(5), 1316–1321. https:// doi.org/10.18203/2320-1770.ijrcog20161008 CR - 3. Calder, P. 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