TY  - JOUR
T1  - Effect of Chemical Castration Using High Osmolarity Solutions on Spermatological Parameters in Rats
TT  - Ratlarda Yüksek Osmolariteli Solüsyonlar Kullanılarak Yapılan Kimyasal Kastrasyonun Spermatolojik Parametrelere Etkisi
AU  - Özer Kaya, Şeyma
AU  - Canpolat, İbrahim
AU  - Akın, Hasan
PY  - 2025
DA  - October
Y2  - 2025
DO  - 10.30607/kvj.1674274
JF  - Kocatepe Veterinary Journal
JO  - kvj
PB  - Afyon Kocatepe University
WT  - DergiPark
SN  - 1308-1594
SP  - 236
EP  - 243
VL  - 18
IS  - 3
LA  - en
AB  - In our study, the changes in spermatological parameters in rats subjected to chemical castration with high osmolarity solutions were investigated.  In the study, they were divided into 8 groups, with 8 rats in each group, and a total of 64 Wistar albino male rats were used. No chemicals were applied to the rats in the control group. Rats in the second group were sterilized surgically. 0.9% physiological saline was administered to the 3rd group, 0.9% physiological saline and 10% calcium chloride to the 4th group, 20% mannitol to the 5th group, 20% mannitol and 10% calcium chloride to the 6th group, 20% dextrose to the 7th group, 20% dextrose and 10% calcium chloride solutions were administered intratesticularly to the 8th group at a dose of 0.1 ml/100gr. Andrological findings compared to the control group; it was determined that there was a significant difference in sperm motility and sperm density (p
KW  - Chemical castration
KW  - spermatological parameters
KW  - rat
KW  - calcium chloride
N2  - Çalışmamızda, yüksek osmolariteli solüsyonlarla kimyasal kısırlaştırma oluşturulan ratlarda spermatolojik parametrelerin değişimi araştırılmıştır. Çalışmada, her grupta 8 rat kullanılarak 8 gruba ayrıldı ve toplam 64 Wistar albino erkek rat kullanıldı. Kontrol grubundaki ratlara herhangi bir kimyasal uygulanmadı. 2. gruptaki ratlar cerrahi olarak kısırlaştırıldı. 3. gruba % 0.9’luk serum fizyolojik, 4. gruba %0.9’luk serum fizyolojik ile %10 kalsiyum klorür, 5. gruba %20 mannitol, 6. gruba %20 mannitol ile %10 kalsiyum klorür, 7. gruba %20 dekstroz, 8. gruba %20 dekstroz ile %10 kalsiyum klorür solüsyonları 0.1ml/100 gr dozda intratestiküler uygulandı. Androlojik bulgular kontrol grubuyla kıyaslandığında; 3, 5, 7. gruplarda sperm motilitesi ve sperma yoğunluğunda (p
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UR  - https://doi.org/10.30607/kvj.1674274
L1  - https://dergipark.org.tr/en/download/article-file/4765140
ER  -