TY - JOUR T1 - Floppy Kid Disease: Diagnostic and Therapeutic Approach in Kids Suffering from FKD in Northern Cyprus AU - Temizel, Ethem Mutlu AU - Sayıner, Serkan AU - Kavukçu, Fatih AU - Karakuş, Adil Ömer PY - 2017 DA - December JF - Journal of Biological and Environmental Sciences JO - JBES PB - Bursa Uludağ University WT - DergiPark SN - 1307-9530 SP - 137 EP - 141 VL - 11 IS - 33 LA - en AB - Floppy Kid Disease (FKD) is a condition which is characterized with metabolic acidosis, generalized anorexia and muscle weakness that can be seen in young goat kids. During the course of an investigation on goat kids suffering from muscle weakness and increased deaths in a goat farm in Cyprus, 10 kids were evaluated. Hematological and biochemical examinations were performed for clinically depressive 5 kids. Also, blood gas analysis were performed for clinically depressive other 5 kids on the next day. As a result of the evaluation, blood pH values of 3 kids were 7.35, 7.33 and 7.26 in blood gas analysis and in addition to that base excess values of these kids were -3.90, -4.0 and -6.8, respectively. Furthermore, BHB values of these kids, which can be generated as a mid-product of D-Lactate, were high and especially the kid with a pH value of 7.26 had BHB level of 160 μmol/L. Following the treatment, only 2 kids died during 1 month of follow-up treatment. This study emphasizes the importance of metabolic acidosis and related parameters in diagnosis of FKD. In general, separation of kids from nannies and giving them oral bicarbonate were thought to be effective for Floppy Kid Disease. KW - Acidosis KW - D-Lactate KW - Kid KW - Bicarbonate CR - Bleul U, Fassbind N, Ghielmetti G, Zoller D, Liesegang A, Hässig M, Wittenbrink MM,Prohaska S. (2001). Quantitative analysis of fecal flora in goat kids with and without floppy kid Disease. J Vet Intern Med 27: 1283–1286. CR - Bleul U, Schwantag S, Stocker H, Corboz L, Grimm F., Engels M, Borel N, Lutz H, Schönmann M, Kähn W. (2006). Floppy kid Disease caused by D-lactic acidosis in goat kids. J Vet Intern Med 20: 1003–1008. CR - Bostedt CKH, Wehrend A. (2010). D-lactate elevation as a cause of metabolic acidosis in newborn goat kids The potential role of milk ingestion as etiopathogenetic factor. Tierarztl Prax Ausg G Grosstiere Nutztiere 38: 371-376. CR - Cebra C, Cebra M. (2012). Disease of the Hematologic, Immunologic, and Lymphatic Systems (Multisystem Disease). Goat and Sheep Medicine. 1st ed. Saunders. 365-366. CR - Harris PA, Coenen M, Frape D, Jeffcott LB, Meyer H. (2009). Nutrition and metabolic Diseases. Goat Medicine. 2nd ed. Wiley-Blackwell., 68. CR - Harris PA, Coenen M, Frape D, Jeffcott LB, Meyer H. (2009). Musculoskeletal System. Goat Medicine. 2nd ed. Wiley-Blackwell.,131. CR - Hoversland AS, Parer T. (1974). Adjustments and Oxygen in Maternal Consumption Blood Pygmy Balance. BiolReprod 10:589–595. CR - Howard LL, Turner LM, Stalis IH, Morris PJ. (2005). Serum gamma-glutamyltransferase as a prognostic indicator of neonatal viability in nondomestic ruminants. J Zoo Wildl Med 36: 239–44. CR - Lorenz I, Gentile A.(2014). D-Lactic Acidosis in Neonatal Ruminants. Vet Clin North Am Food Anim Pract 30: 317–331. Lorenz I, Hartmann I, Gentile A.(2003). Determination of D-lactate in calf serum samples - An automated enzymatic assay. Comp Clin Path12: 169–171. CR - Omole OO, Nappert G, Naylor JM, Zello G. (2001). Both L- and D-lactate contribute to metabolic acidosis in diarrheic calves. J Nutr 131: 2128–2131. CR - Temizel EM, Senturk S, Kasap S. (2009). Clinical, haematological and biochemical findings in Saanen goat kids with naturally occurring heat stroke. Tierarztl Prax Ausg G Grosstiere Nutztiere 37: 236–241. CR - Tremblay RR, Butler DG, Allen JW, Hoffman M. (1991). Metabolic acidosis without dehydration in seven goat kids. Can Vet J 32: 308–10. CR - Yalcin E, Temizel EM, Yalcin A, Carkungoz E. (2010) Relationship with gamma glutamyl transferase activity and glutaraldehyde coagulation test of serum immunoglobulin G concentration in newborn goat kids. Small Rumin 93: 61–63. UR - https://dergipark.org.tr/en/pub/jbes/issue//1678398 L1 - https://dergipark.org.tr/en/download/article-file/4783189 ER -