TY - JOUR T1 - Alterations of lipid profile in overweight and obese dogs AU - Gökçe, Halil İbrahim AU - Sarikaya, Ecenur Esra PY - 2025 DA - April Y2 - 2024 DO - 10.24880/meditvetj.1687700 JF - Mediterranean Veterinary Journal JO - MeditVetJ PB - Burdur Mehmet Akif Ersoy University WT - DergiPark SN - 3023-8447 SP - 410 EP - 415 VL - 10 IS - 1 LA - en AB - The purpose of the study was to determine the alterations of lipid profile in overweight and obese dogs. Obesity is defined as abnormal or excessive fat accumulation in the body. It is a chronic health problem for both human and animals. Dogs with restricted movements and fed high-energy diets are particularly at a high risk. In the study, 30 dogs of different ages, breeds and genders were used. Dogs were divided into 3 groups equally as ideal weight, overweight and obese according to the body condition score (BCS) chart. Serum samples were collected from all dogs and used to analyze lipid profile parameters using a biochemistry analyzer. In the study, significant increases were detected in total-C (p<0.01), VLDL (p<0.05), and LDL (p<0.05) in obese dogs compared to those of both control and overweight dogs (Table 1). The numbers of dogs with increases in lipid profile parameters were higher in obese dogs than in overweight dogs. In obese dogs, very strong positive correlations were also detected between some of lipid profile parameters. In conclusion, it has been revealed that there are significant alterations in lipid profile parameters in both overweight and obese dogs. The levels of these changes are thought to be related to the severity and progression of obesity in dogs. Presence of strong correlations between lipid profile parameters indicated that total-C, HDL, VLDL, LDL, total-C/LDL and Tg values can be used to evaluate alterations in lipid profile parameters in obese dogs. 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