@article{article_1688124, title={Our Experience of Endovascular Treatment in Patients with Acute Dissection and Major Vessel Occlusion}, journal={Journal of Cukurova Anesthesia and Surgical Sciences}, volume={8}, pages={175–180}, year={2025}, DOI={10.36516/jocass.1688124}, author={Altuntaş Kaya, Fatma and Uysal Kocabaş, Zehra and Aykaç, Özlem and Özdemir, Atilla Özcan}, keywords={Interventional Neurology, Acute stroke, Dissection, Mechanical Thrombectomy}, abstract={Intravenous thrombolytic therapy is an effective and safe method in the treatment of acute ischemic stroke due to dissection. Our knowledge about the clinical results and reperfusion rates of the endovascular treatment of dissection associated with intracranial vessel occlusion is limited. In our study, we aimed to present our patients with acute dissection in the etiology for which we applied endovascular treatment. Patients who underwent endovascular treatment of acute ischemic stroke due to a major vessel occlusion secondary to extracranial or intracranial vessel dissection were extrapolated from Eskisehir Osmangazi Stroke Center Database between January 2015 and May 2020. Patients’ age, gender, symptom time, time of arrival to the emergency room, administration of thrombolytic therapy, admission NIHSS score, ASPECT, etiological diagnoses, thrombectomy method, recanalization rate, post-procedure intracerebral bleeding (SITS-MOST), modified Rankin score at discharge and 3 months later were recorded. A total of 13 patients with a mean age of 43 ± 9.84 years were included in the study. Of the patients, 46.1% were male (n=6) and 53.8% were female (n=7). Two patients had a history of blunt trauma within the last week. In diagnostic digital subtraction angiography (DSA), it was observed that 12 patients had internal carotid artery dissection. One patient had vertebrobasilar occlusion due to dissection of V4 segment of vertebral artery. TPA was applied to 15% (n=2) of the patients. There were contraindications for tPA in 30% of the patients (n=4). Thromboaspiration method was applied in 46.1% of the patients (n=6) as the first technique in the procedure (Figure 4). Isolated stent was applied in 23% of the patients (n=3) as the first technique. Combined technique was applied in 30% (n=4) of the patients. First pass recanalization rate was found to be 38.4% (n=5). Two or more intracranial procedures had to be performed in 58.3% of the patients (n=7). The rate of complete recanalization (TICI 2b-3) was 92.3% (n=12). Recanalization could not be achieved in one patient. First pass recanalization rate was 38.4% (n=5). Clinical progression and worsening of symptoms due to bleeding (NIHSS> 4) were not observed. The rate of patients who were living independently (mRS ≤2) was 76.9% (n=10). Endovascular treatment of acute ischemic stroke due to dissection is effective and safe. More studies are needed to evaluate the effectiveness of endovascular therapy and to identify techniques that provide better clinical outcomes.}, number={2}, publisher={Merthan TUNAY}