TY  - JOUR
T1  - Development of electrochemistry-based biosensors in medical field
AU  - Taşkın, Ergin
AU  - Öztürk Doğan, Hülya
PY  - 2025
DA  - December
Y2  - 2025
JF  - NanoEra
JO  - NanoEra
PB  - Ataturk University
WT  - DergiPark
SN  - 2792-0666
SP  - 71
EP  - 74
VL  - 5
IS  - 2
LA  - en
AB  - Electrochemistry, as a subdivision of chemistry, describes the kind of physical chemistry where one studies the reactions occurring chemically and expresses these as electrical processes, playing an important role in the diagnosis and therapeutic procedures of diseases in the health field, particularly modern medicine. This art of science stands equally important in diagnosis and treatment, while developing biosensors at a preliminary stage, with glucose biosensors developed first and, in later stages, have seen applications for widespread use in assessing biomarkers for cholesterol and cancer, and are still in use to date. Therefore, with the developments in nanotechnology in this century, the development and AI integration of electrochemistry-based biosensors have marginally placed and strongly act as a bright hope in diagnosis and treatment. Biosensors stand as big players regarding monitoring diseases in medicine while offering early diagnosis and therapeutic approaches, like controlled drug release, that need more precision and specificity. More than this, this process allows the construction of less heavy and highly portable personal health monitoring systems. The present work aims to analyze the development of electrochemistry in health, its current situation, and developments with promise for the future.
KW  - Electrochemistry
KW  - Biosensor
KW  - Nanotechnology
CR  - 1. Theyagarajan K, Kim YJ. Recent Developments in the Design and Fabrication of Electrochemical Biosensors Using Functional Materials and Molecules. Biosensors. 2023;13(4):424. doi:10.3390/bios13040424
CR  - 2. Rackus DG, Shamsi MH, Wheeler AR. Electrochemistry, biosensors and microfluidics: a convergence of fields. Chem Soc Rev. 2015;44(15):5320-5340. doi:10.1039/C4CS00369A
CR  - 3. Bard AJ, Murray RW. Electrochemistry - Introduction. In: Proceedings of the National Academy of Sciences of the United States of America. Vol 109. Natl Acad Sciences 2101 Constitution Ave NW, Washington, DC 20418 USA; 2012:11484-11486.
CR  - 4. Cui H, Xin X, Su J, Song S. Research Progress of Electrochemical Biosensors for Diseases Detection in China: A Review. Biosensors. 2025;15(4):231. doi:10.3390/bios15040231
CR  - 5. Clark L, Lyons C. Electrode systems for continuous monitoring in cardiovascular surgery. Ann NY Acad Sci. 1962;102:29-45.
CR  - 6. Shoaib A, Darraj A, Khan ME, et al. A Nanotechnology-Based Approach to Biosensor Application in Current Diabetes Management Practices. Nanomaterials. 2023;13(5):867. doi:10.3390/nano13050867
CR  - 7. Justino CIL, Freitas AC, Pereira R, Duarte AC, Rocha Santos TAP. Recent developments in recognition elements for chemical sensors and biosensors. TrAC Trends Anal Chem. 2015;68(5):2-17. doi:10.1016/j.trac.2015.03.006
CR  - 8. Majdinasab M, Mitsubayashi K, Marty JL. Optical and Electrochemical Sensors and Biosensors for the Detection of Quinolones. Trends Biotechnol. 2019;37(8):898-915. doi:10.1016/j.tibtech.2019.01.004
CR  - 9. Bordbar MM, Sheini A, Hashemi P, Hajian A, Bagheri H. Disposable Paper-Based Biosensors for the Point-of-Care Detection of Hazardous Contaminations—A Review. Biosensors. 2021;11(9):316. doi:10.3390/bios11090316
CR  - 10. Ronkainen NJ, Halsall HB, Heineman WR. Electrochemical biosensors. Chem Soc Rev. 2010;39(5):1747. doi:10.1039/b714449k
CR  - 11. Perumal V, Hashim U. Advances in biosensors: Principle, architecture and applications. J Appl Biomed. 2014;12(1):1-15. doi:10.1016/j.jab.2013.02.001
CR  - 12. Kilic NM, Singh S, Keles G, Cinti S, Kurbanoglu S, Odaci D. Novel Approaches to Enzyme-Based Electrochemical Nanobiosensors. Biosensors. 2023;13(6):622. doi:10.3390/bios13060622
CR  - 13. Lee JE, Pack SP. Recent Progress in DNA Biosensors: Target-Specific and Structure-Guided Signal Amplification. Biosensors. 2025;15(8):476. doi:10.3390/bios15080476
CR  - 14. Bastos-Soares EA, Sousa RMO, Gómez AF, et al. Single domain antibodies in the development of immunosensors for diagnostics. Int J Biol Macromol. 2020;165:2244-2252. doi:10.1016/j.ijbiomac.2020.10.031
CR  - 15. Wang W, He Y, He S, et al. A Brief Review of Aptamer-Based Biosensors in Recent Years. Biosensors. 2025;15(2):120. doi:10.3390/bios15020120
CR  - 16. Bagotsky VS. Elektrokimyanın Temelleri. 2nd ed. (Tapan NA, Aksu ML, eds.). Nobel Akademik Yayıncılık; 2015.
17. Kissinger PT, Bott AW. Electrochemistry for the non-electrochemist. Curr Sep. 2002;20(2):51-54.
CR  - 18. Keskin M, Arslan F. Biyosensörler. Gazi Üniversitesi Fen Fakültesi Derg. 2020;1(1-2):51-60.
CR  - 19. Özbek Z. Kolesterol Tayini için Biyosensör Geliştirilmesi. Afyon Kocatepe Üniversitesi Uluslararası Mühendislik Teknol ve Uygulamalı Bilim Derg. 2023;6(1):63-74. doi:10.53448/akuumubd.1296685
CR  - 20. Watson CJ, Ledwidge MT, Phelan D, et al. Proteomic Analysis of Coronary Sinus Serum Reveals Leucine-Rich α2-Glycoprotein as a Novel Biomarker of Ventricular Dysfunction and Heart Failure. Circ Hear Fail. 2011;4(2):188-197. doi:10.1161/CIRCHEARTFAILURE.110.952200
CR  - 21. Maurer M, Burri S, de Marchi S, et al. Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome. Int J Cardiol. 2010;141(1):32-38. doi:10.1016/j.ijcard.2008.11.131
CR  - 22. Turgut B. Biosensors and Healthcare. J Acad Soc Resour. 2023;8(47):2492-2498. doi:10.29228/ASRJOURNAL.68930
CR  - 23. Cunha DR, Segundo MA, Quinaz MB. Electrochemical methods for evaluation of therapeutic monoclonal antibodies: A review. Biosens Bioelectron. 2025;271:116988. doi:10.1016/j.bios.2024.116988
CR  - 24. Özçelik E, Erdal M, Özsoy Erginer Y. Recent Technologies in Controlled Release Drug Delivery. J Adv Res Heal Sci. 2022;5(2):122-129. doi:10.26650/JARHS2022-1122852
CR  - 25. Sunal KS. Amperometrik ve İmpedimetrik Biyosensörler Ile Farklı Tip Kanserlerin Biyobelirteci Olan CD-105 (Endoglin) Tayini. Erciyes University; 2021.
CR  - 26. Özoğlu Ö, Ünal MA, Altuntaş EG. Biosensors: Lactate Biosensors in Food and Health Field. Turkish J Life Sci. 2017;2(2):180-193.
CR  - 27. Eabd Alrida S, Obed O, Taha E, Abdullah T, Hathal M, Somogyi V. Applications of artificial intelligence in nanotechnology. Eng Technol J. 2024;42(9):1193-1209. doi:10.30684/etj.2024.148957.1736
CR  - 28. Chugh V, Basu A, Kaushik A, Manshu, Bhansali S, Basu AK. Employing nano-enabled artificial intelligence (AI)-based smart technologies for prediction, screening, and detection of cancer. Nanoscale. 2024;16(11):5458-5486. doi:10.1039/D3NR05648A
UR  - https://dergipark.org.tr/en/pub/nanoera/article/1694527
L1  - https://dergipark.org.tr/en/download/article-file/4848207
ER  -