TY  - JOUR
T1  - Management of Wound Site Infections
AU  - Kurtoğlu, Muhammet
AU  - Babayev, Huseyn
PY  - 2025
DA  - August
Y2  - 2025
DO  - 10.47493/abantmedj.1699572
JF  - Abant Medical Journal
JO  - Abant Med J
PB  - Bolu Abant Izzet Baysal University
WT  - DergiPark
SN  - 1305-4392
SP  - 112
EP  - 129
VL  - 14
IS  - 2
LA  - en
AB  - Wound infections are a significant problem in clinical practice, affecting millions of people worldwide. These infections contribute to prolonged hospital stays, increased healthcare costs, and increased morbidity and mortality. This review provides a comprehensive review of various wound types and their associated changing etiological agents. Special attention is paid to antimicrobial resistance (AMR), a growing global public health problem that complicates wound management. We discuss how genetic factors and specific virulence mechanisms enable pathogens to resist standard antimicrobial treatments, how these challenges lead to biofilm formation, and how chronic wounds are worsened by different microorganisms. Strategies for achieving accurate and timely diagnosis are discussed, including new diagnostic approaches that could revolutionize clinical practice. Antimicrobial treatment methods and other treatment methods (such as debridement, negative pressure, hyperbaric oxygen) are reviewed in detail. In addition, the importance of infection control practices, antimicrobial stewardship, patient education, and infection prevention and control methods are emphasized. Future perspectives focus on identifying new antimicrobials, alternative therapies, improved diagnostic tools, better understanding of AMR mechanisms, and emphasizing the urgent need for integrative and personalized approaches to wound management. By synthesizing the current state of knowledge and identifying gaps for further research, this review highlights the importance of collaborative, multidisciplinary efforts to alleviate the burden of wound infections and counter the rise of antimicrobial resistance.
KW  - Wound infections
KW  - antimicrobial resistance
KW  - biofilm
KW  - chronic wounds
KW  - multidrug-resistant pathogens
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UR  - https://doi.org/10.47493/abantmedj.1699572
L1  - https://dergipark.org.tr/en/download/article-file/4871378
ER  -