TY - JOUR T1 - Magnesium Level in the Mortality Prediction of Community-acquired Pneumonia Patients AU - Acar, Ethem AU - Gökçen, Hasan AU - Demir, Ahmet AU - Yıldırım, Birdal PY - 2022 DA - June DO - 10.4274/meandros.galenos.2021.47855 JF - Meandros Medical And Dental Journal JO - Meandros Med. Den. j. PB - Aydin Adnan Menderes University WT - DergiPark SN - 2149-9063 SP - 155 EP - 161 VL - 23 IS - 2 LA - en AB - Objective: We aimed to examine the contribution of pneumonia severity index and blood magnesium (Mg) level of community-acquired pneumonia (CAP) patients who received inpatient treatment in our hospital to the mortality of the cases. Materials and Methods: Our study is a retrospective study in which we applied to the emergency department (ED) of our hospital in 2018, with the diagnosis of CAP, and were hospitalized to the wards or intensive care unit (ICU). Results: A total of 279 patients with CAP were enrolled in this study. All-cause mortality on the 28th day of follow-up was 13.6%. There were statistically significant results between the 2 groups (survivors and non-survivors), which were classified based on their 28-day mortality rates, in terms of the Mg, pneumonia severity index (PSI), and confusion, urea, respiratory rate, blood pressure, age >65 years (CURB-65) values. Moreover, the optimal Mg cut-off for predicting 28-day mortality at the time of ED admission was determined to be 1.90 mg/dL, with 71% sensitivity, 73% specificity, and 73% accuracy. ROC analysis revealed that the areas of Mg under the AUC in terms of 28-day mortality were 0.778. Thirty-eight patients died during the first 28-day period. Of these, 27 (64,2%) had Mg level KW - Community-acquired pneumonia KW - magnesium level KW - mortality KW - emergency medicine CR - 1. Turkey Statistical Institute, Health Statistics 2004. Available from: [http://www.tuik.gov.tr](http://www.tuik.gov.tr). CR - 2. Tokgoz Akyil F, Yalcinsoy M, Hazar A, Cilli A, Celenk B, Kılıc O, et al. Prognosis of hospitalized patients with community-acquired pneumonia. Pulmonology 2018; 24: 164-9. CR - 3. Madhu S, Augustine S, Ravi Kumar YS, Kauser MM, Vagesh Kumar SR, Jayaraju BS. Comparative study of CURB-65, Pneumonia Severity Index and IDSA/ATS scoring systems in community acquired pneumonia in an Indian tertiary care setting. Int J Adv Med 2017; 4: 693-700. CR - 4. Cheungpasitporn W, Thongprayoon C, Qian Q. Dysmagnesemia in Hospitalized Patients: Prevalence and Prognostic Importance. Mayo Clin Proc 2015; 90: 1001-10. CR - 5. Cheungpasitporn W, Thongprayoon C, Bathini T, Hansrivijit P, Vaitla P, Medaura J, et al. Impact of admission serum magnesium levels on long-term mortality in hospitalized patients. Hosp Pract (1995) 2020; 48: 80-5. CR - 6. Nasser R, Naffaa ME, Mashiach T, Azzam ZS, Braun E. The association between serum magnesium levels and community-acquired pneumonia 30-day mortality. BMC Infect Dis 2018; 18: 698. CR - 7. Acar E, Gokcen H, Demir A, Yildirim B. Comparison of inflammation markers with prediction scores in patients with community-acquired pneumonia. Bratisl Lek Listy 2021; 122: 418-23. CR - 8. Thongprayoon C, Cheungpasitporn W, Hansrivijit P, Thirunavukkarasu S, Chewcharat A, Medaura J, et al. Association of serum magnesium level change with in-hospital mortality. BMJ Evid Based Med 2020; 25: 206-12. CR - 9. Velissaris D, Karamouzos V, Pierrakos C, Aretha D, Karanikolas M. Hypomagnesemia in Critically Ill Sepsis Patients. J Clin Med Res 2015; 7: 911-8. CR - 10. Chen M, Sun R, Hu B. The influence of serum magnesium level on the prognosis of critically ill patients. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015; 27: 213-7. CR - 11. Guerin C, Cousin C, Mignot F, Manchon M, Fournier G. Serum and erythrocyte magnesium in critically ill patients. Intensive Care Med. 1996; 22: 724-7. CR - 12. Celi LA, Scott DJ, Lee J, Nelson R, Alper SL, Mukamal KJ, et al. Association of hypermagnesemia and blood pressure in the critically ill. J Hypertens. 2013; 31: 2136-41. CR - 13. Marti C, Garin N, Grosgurin O, Poncet A, Combescure C, Carballo S, et al. Prediction of severe community-acquired pneumonia: a systematic review and meta-analysis. Crit Care. 2012; 16: R141. UR - https://doi.org/10.4274/meandros.galenos.2021.47855 L1 - https://dergipark.org.tr/en/download/article-file/4898145 ER -