@article{article_1706605, title={Waste Burnt Tyres Induced Histomorphological Alterations in the Visceral Organs and Cerebellum of Juvenile Cat Fish (Clarias gariepinus)}, journal={Turkish Journal of Science and Technology}, volume={21}, pages={25–34}, DOI={10.55525/tjst.1706605}, author={Sulaiman, Yusuf and Omirinde, Jamiu and Azeez, Idris Ayodeji and Audu, Bala}, keywords={Burnt tyres, visceral organs, cerebellum, histology, sub-lethal concentration, Clarias gariepinus}, abstract={The practice of burning waste tyres by the locals to obtain steel and rod is usually accompanied with the release of toxic fumes directly into the atmosphere or transport of leachate of particulate matters by the surface run-off into the aquatic environments where they impact serious ecotoxicological damage. This study was conducted to investigate the histomorphological changes in the visceral organs of Clarias gariepinus juveniles exposed to sub-lethal concentrations (SLCs) of water soluble fractions (WSFs) of waste burnt tyres (WBTRs). The SLCs of WBTRs were obtained by dividing LC50 of 11.22g/L by 1/3th, 1/6 th, 1/9 th , 1/12 th , 1/24 th and 1/48 th respectively. C. gariepinus juveniles of mixed sexes (Average weight: Male (M) - 46.9±0.3.44g; Female (F) - 26.69 ± 3.46g; Average length: M - 14.08±0.54cm; F -16.29±0.51cm) were exposed to SLCs (0.00, 0.23, 0.47, 0.94, 1.87 and 3.74g/L) of WBTRs for 58 days in duplicate. Sequel to the completion of the experiment, catfish were sacrificed using cervical dislocation method. The gills, liver, kidneys, testes, ovaries, brain and intestine were excised and routinely processed for histological studies. The sub lethal grades of WBTRs distinctly induced dose-dependant histo-architectural damages in the different organs including moderate to severe gill epithelial cell hypertrophy and lamellar venous congestion, hepatocellular degeneration and sinusoidal congestion, moderate cellular infiltration into the renal interstitium, reduced seminiferous tubular luminal contents, cerebellar Purkinje cell degeneration and gliosis. Waste burnt tyres demonstrated to be very toxic to fish and therefore, preventive measures should be taken to avoid the burning of waste tyres near riparian vegetation and aquatic ecosystems.}, number={1}, publisher={Fırat University}, organization={University of Jos Institutional Based Research (IBR) Tertiary Education Trust Fund Research Grant.}