TY - JOUR T1 - Vertebral Artery Origin Stenosis in Patients with Posterior Circulation Strokes Due to Large Artery Atherosclerosis TT - Büyük Arter Aterosklerozuna Bağlı Posterior Dolaşımda İnmesi Olan Hastalarda Vertebral Arter Orjin Stenozları AU - Erdoğan, Seyda AU - Şahin, Turgut AU - Sorgun, Mine Hayriye AU - Karaaslan, Fatma Tuğra AU - Özaydın Aksun, Zerin AU - Yalap, Ömer Eray AU - Bulut, Onur AU - Ölmez, Büşra AU - Yılmaz, Abdullah Yasir AU - Yavuz, Zehra AU - Önder, Canan AU - Nadirova, Aygül AU - Erdoğan, Mustafa AU - Aslanbaba, Eda AU - Allahverdiyev, Tehran AU - Togay Işıkay, Canan PY - 2024 DA - October Y2 - 2024 DO - 10.4274/atfm.galenos.2024.59013 JF - Ankara Üniversitesi Tıp Fakültesi Mecmuası PB - Ankara University WT - DergiPark SN - 0365-8104 SP - 243 EP - 247 VL - 77 IS - 3 LA - en AB - Objectives: The origin of the extracranial vertebral artery (V1 segment) is a common site for large artery atherosclerosis (LAA). The aim of this study was to determine the risk factors, prevalence and prognosis of the patients presented with acute ischemic stroke due to vertebrobasilar atherosclerosis and additional V1 stenosis. Materials and Methods: We reviewed the charts of 957 patients who were admitted with acute ischemic stroke between the dates January 2011 and May 2017, and selected cases with stroke related to posterior circulation (PC) atherosclerosis. The demographic data, risk factors, National Institutes of Health Stroke Scale (NIHSS) scores at admission, and modified Rankin scores (mRS) in the follow-up period were recorded.Results: There were 80 (8.36%) patients with acute ischemic stroke in the PC due to LAA. Thirty (37.5%) patients [9 females (30%), mean age 67.4±14.3 years] had V1 stenosis. No between group differences in the history of vascular risk factors and mRS scores during the follow-up period were observed (p>0.05). In logistic regression analysis, the admission NIHSS score was higher in patients with V1 stenosis than others (p=0.022).Conclusion: In our registry, more than one third of patients with acute PC stroke due to LAA had stenosis in the origin of the vertebral artery. The patients with coexisting V1 stenosis presented with relatively severe stroke. KW - Vertebral artery origin KW - posterior circulation strokes KW - large artery atherosclerosis CR - 1. Bogousslavsky J, Van Melle G, Regli F. The Lausanne Stroke Registry: analysis of 1,000 consecutive patients with first stroke. Stroke. 1988;19:1083-1092. CR - 2. Yamamoto Y, Georgiadis AL, Chang HM, et al. Posterior cerebral artery territory infarcts in the New England Medical Center Posterior Circulation Registry. Arch Neurol. 1999;56:824-832. CR - 3. Caplan L. Posterior circulation ischemia: then, now, and tomorrow. The Thomas Willis Lecture-2000. Stroke. 2000;31:2011-2023. CR - 4. Mazighi M, Labreuche J, Gongora-Rivera F, et al. 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