TY  - JOUR
T1  - Elsberg Syndrome: One of the Causes of Cauda Equina Syndrome - A Case Series and Review of the Literature
TT  - Elsberg Sendromu: Kauda Ekina Sendromunun Nedenlerinden Biri - Olgu Serisi ve Literatürün Gözden Geçirilmesi
AU  - Genç, Aysun
PY  - 2024
DA  - April
DO  - 10.4274/atfm.galenos.2023.36693
JF  - Ankara Üniversitesi Tıp Fakültesi Mecmuası
PB  - Ankara University
WT  - DergiPark
SN  - 0365-8104
SP  - 373
EP  - 377
VL  - 76
IS  - 4
LA  - en
AB  - Elsberg syndrome (ES) is a rare syndrome characterized by acute or subacute lumbosacral radiculitis and myelitis confined to the lower spinalcord, following an acute or reactivation viral infection. Reported complaints are urinary retention, bowel incontinence, radicular pain and muscleweakness. It is associated with Herpes simplex type 2 infections or reactivation from dorsal root ganglia, there are also cases reported with acutewest Nile virus, varicella zoster virus and severe acute respiratory syndrome coronavirus 2. Clinicians do not generally consider this syndrome inthe differential diagnosis of acute cauda equina syndrome, and therefore, appropriate diagnostic approaches are missed. Sarcoidosis, lymphoma,vasculitis, other sources of infection and dural arteriovenous fistula are also included in the differential diagnosis.In order to draw attention to ES, which is a post viral inflammatory condition, two cases presenting acute cauda equina syndrome findings anddiagnosed with ES will be presented.
KW  - Elsberg Syndrome
KW  - Herpes Simplex Type 2
KW  - Miyelitis
N2  - Elsberg sendromu (ES), akut veya reaktif bir viral enfeksiyonu takiben omurilik alt bölgesinde sınırlı,akut veya subakut lumbosakral radikülit ve miyelitile karakterize nadir bir sendromdur. Bildirilen semptomlar idrar retansiyonu, bağırsak inkontinansı, radiküler ağrı ve kas güçsüzlüğüdür. Herpessimpleks tip 2 enfeksiyonları veya dorsal kök gangliyonlarından reaktivasyon ile ilişkilidir, ayrıca akut batı Nil virüsü, varisella zoster virüsü ve Şiddetliakut solunum yolu sendromu koronavirüs-2 ile bildirilen olgular da vardır. Klinisyenler genellikle bu sendromu akut kauda ekina sendromununayırıcı tanısında değerlendirmez ve bu nedenle uygun tanısal yaklaşımlar gözden kaçar. Sarkoidoz, lenfoma, vaskülit, diğer enfeksiyon kaynakları vedural arteriyovenöz fistül de ayırıcı tanıda yer almaktadır. Post viral enflamatuvar bir durum olan ES’ye dikkat çekmek amacıyla akut kauda ekuinasendromu bulguları gösteren ve ES tanısı alan iki olgu sunulacaktır.
CR  - 1. Hawkes MA, Toledano M, Kaufmann TJ, et al. West Nile Neuroinvasive
Disease Presenting as Elsberg Syndrome. Neurologist. 2018;23:152-154.
CR  - 2. Savoldi F, Kaufmann TJ, Flanagan EP, et al. Elsberg syndrome: A rarely
recognized cause of cauda equina syndrome and lower thoracic myelitis.
Neurol Neuroimmunol Neuroinflamm. 2017;4:e355.
CR  - 3. Abrams RMC, Desland F, Lehrer H, et al. A Case of Elsberg Syndrome in the
Setting of Asymptomatic SARS-CoV-2 Infection. J Clin Neuromuscul Dis.
2021;22:228-231.
CR  - 4. Suarez-Calvet M, Rojas-Garcia R, Querol L, et al. Polyradiculoneuropathy
associated to human herpesvirus 2 in an HIV-1-infected patient (Elsberg
syndrome): case report and literature review. Sex Transm Dis. 2010;37:123-
125.
CR  - 5. Yoritaka A, Ohta K, Kishida S. Herpetic lumbosacral radiculoneuropathy
in patients with human immunodeficiency virus infection. Eur Neurol.
2005;53:179-181.
CR  - 6. Santos DH, Carneiro de Oliveira RM, Junior WRF, et al. Myelorradiculitis
due to Varicella Zoster (Elsberg syndrome) as the first symptom of HIV in a
patient with Crohn’s disease in use of Infliximab. Mult Scler Relat Disord.
2021;47:102643.
CR  - 7. Bhagat YV, Yunasan E, Alzedaneen Y, et al. Treatment of Elsberg Syndrome
Causes Fever of Unknown Origin Attributable to Drug Reaction. Cureus.
2021;13:e18510.
CR  - 8. Choudhury NA, Castrodad-Molina RM, Hutton GJ, et al. Elsberg syndrome
following acute immunosuppressive treatment for multiple sclerosis
relapse. Mult Scler Relat Disord. 2022;58:103498.
CR  - 9. Saito H, Ebashi M, Kushimoto M, et al. Elsberg syndrome related to varicella
zoster virus infection with painless skin lesions in an elderly woman
with poorly controlled type 2 diabetes mellitus. Ther Clin Risk Manag.
2018;14:1951-1954.
CR  - 10. Desai R, Welsh CT, Schumann SO 3rd. Elsberg Syndrome, Lumbosacral
Radiculopathy, and Myelitis Due to Herpes Zoster in a Patient
With Smoldering Myeloma. J Investig Med High Impact Case Rep.
2022;10:23247096211063348.
CR  - 11. Tavanaei R, Oraee-Yazdani M, Allameh F, et al. Cauda equina syndrome
due to herpes simplex virus type 2-associated meningoradiculitis (Elsberg
syndrome) after posterior lumbar spinal fusion surgery: Case report and
review of literature. Clin Neurol Neurosurg. 2021;205:106624
UR  - https://doi.org/10.4274/atfm.galenos.2023.36693
L1  - https://dergipark.org.tr/en/download/article-file/4914028
ER  -