TY  - JOUR
T1  - The clinical characteristics of influenza and other viral respiratory infections in the intensive care unit: A one-year single-center retrospective study
TT  - Yoğun bakım ünitesinde influenza ve diğer solunum yolu viral enfeksiyonlarının klinik özellikleri: Bir yıllık tek merkezli retrospektif çalışma
AU  - Alparslan, Volkan
AU  - Güler, Özlem
AU  - Kutlu, Samet
AU  - İzgin Avcı, İpek
AU  - Karadenizli, Aynur
AU  - Baykara, Nur
AU  - Kuş, Alparslan
PY  - 2025
DA  - June
Y2  - 2025
DO  - 10.53446/actamednicomedia.1712079
JF  - Acta Medica Nicomedia
JO  - Acta Med Nicomedia
PB  - Kocaeli University
WT  - DergiPark
SN  - 2717-8994
SP  - 212
EP  - 216
VL  - 8
IS  - 2
LA  - en
AB  - Objective: The aim of this study was to evaluate the clinical features and prognostic factors associated with mortality in respiratory viral infections in intensive care unit patients.Methods: This retrospective, single-centre study included adult patients aged ≥18 years who were admitted to the intensive care unit of Kocaeli University Faculty of Medicine between March 2024 and March 2025 and whose respiratory viral agent was detected by BioFire® Respiratory 2.1 Plus Panel test. Demographic data, clinical and pneumonia scoring systems (APACHE II, SOFA, PSI, CURB-65), laboratory parameters and patient prognosis (survived/non survived) were analysed.Results: A total of 547 out of 2719 intensive care unit patients underwent respiratory panel, and at least one viral agent was detected in 95 (17.4%) of them. The most frequently detected viruses were rhinovirus/enterovirus (n=22), SARS-CoV-2 (n=15) and influenza A-H3 (n=23). The intensive care unit mortality rate was 54.3% in viral positive patients. APACHE II, SOFA, PSI and CURB-65 scores as well as urea and procalcitonin levels were found to be significantly higher in patients with non-survived (p
KW  - Respiratory viruses
KW  - intensive care unit
KW  - influenza
KW  - COVID-19
KW  - APACHE II
KW  - SOFA
N2  - Amaç: Bu çalışmanın amacı, yoğun bakım hastalarında saptanan solunum yolu viral enfeksiyonlarının klinik özelliklerini ve mortalite ile ilişkili prognostik faktörleri değerlendirmektir.Yöntem: Bu retrospektif, tek merkezli çalışmaya, Mart 2024 – Mart 2025 tarihleri arasında Kocaeli Üniversitesi Tıp Fakültesi yoğun bakım ünitesine kabul edilen ve BioFire® Respiratory 2.1 Plus Panel testi ile solunum yolu viral etkeni saptanan ≥18 yaş erişkin hastalar dahil edildi. Demografik veriler, klinik ve pnömoni skorlama sistemleri (APACHE II, SOFA, PSI, CURB-65), laboratuvar parametreleri ve hasta prognozu (yaşam/exitus) analiz edildi.Bulgular: Toplam 2719 yoğun bakım hastasından 547’sine solunum paneli uygulanmış, bunların 95’inde (%17,4) en az bir viral etken saptanmıştır. En sık tespit edilen virüsler rhinovirüs/enterovirüs (n=22), SARS-CoV-2 (n=15) ve influenza A-H3 (n=23) olmuştur. Viral pozitif hastalarda yoğun bakım mortalite oranı %54,3 bulunmuştur. Ölen hastalarda APACHE II, SOFA, PSI ve CURB-65 skorlarının yanı sıra üre ve prokalsitonin düzeylerinin anlamlı derecede yüksek olduğu görülmüştür (p
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UR  - https://doi.org/10.53446/actamednicomedia.1712079
L1  - https://dergipark.org.tr/en/download/article-file/4927263
ER  -