TY  - JOUR
T1  - Predictive Performance of Admission Hematological Parameters for Adverse Clinical Outcomes in Acute Cholangitis
TT  - Akut Kolanjit Hastalarında Olumsuz Klinik Sonuçları Öngörmede Başvuru Hematolojik Parametrelerinin Tahmin Gücü
AU  - Çomoğlu, Mustafa
AU  - Altıparmak, Emin
AU  - Çamlı, Hüseyin
AU  - Ateş, İhsan
PY  - 2025
DA  - September
Y2  - 2025
DO  - 10.65092/autfm.1714443
JF  - Ankara Üniversitesi Tıp Fakültesi Mecmuası
PB  - Ankara University
WT  - DergiPark
SN  - 0365-8104
SP  - 187
EP  - 197
VL  - 78
IS  - 3
LA  - en
AB  - Objectives: This study aimed to evaluate the prognostic performance of hematological parameters, including red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR), in patients with acute cholangitis (AC).Materials and Methods: In this prospective study, 202 patients diagnosed with AC between December 2023 and August 2024 were included. The predictive performance of admission hematological parameters for clinical outcomes, including in-hospital mortality, bacteremia, need for inotropic support, prolonged hospital stay, intensive care unit (ICU) admission, and prolonged ICU stay, was assessed and compared.Results: Among the 202 patients, 16 (7.9%) died during hospitalization. Multivariate regression analysis identified RDW as an independent risk factor for in-hospital mortality (odds ratio [OR]: 2.25, 95% confidence interval [CI]: 1.48–3.42, p
KW  - acute cholangitis
KW  - hematological parameters
KW  - mortality
N2  - Amaç: Bu çalışma, akut kolanjit (AC) hastalarında eritrosit dağılım genişliği (RDW) ve nötrofil-lenfosit oranı (NLR) dahil olmak üzere hematolojik parametrelerin prognostik performansını değerlendirmeyi amaçlamıştır.Gereç ve Yöntem: Bu prospektif çalışmaya, Aralık 2023 ile Ağustos 2024 tarihleri arasında AC tanısı almış 202 hasta dâhil edildi. Başvuru anındaki hematolojik parametrelerin, hastane içi mortalite, bakteriyemi, inotrop ihtiyacı, uzamış hastane yatışı, yoğun bakım (ICU) yatışı ve uzamış ICU yatışı gibi klinik sonuçları öngörme gücü değerlendirildi ve karşılaştırıldı.Bulgular: Çalışmaya dâhil edilen 202 hastanın 16’sı (%7.9) hayatını kaybetti. Çok değişkenli regresyon analizinde RDW, hastane içi mortalite için bağımsız bir risk faktörü olarak bulundu (odds ratio [OR]: 2.25, %95 güven aralığı [GA]: 1.48–3.42, p
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UR  - https://doi.org/10.65092/autfm.1714443
L1  - https://dergipark.org.tr/en/download/article-file/4936603
ER  -