TY - JOUR T1 - AKUT MYOKARD İNFAKTÜŞÜNDE HDL DÜZEYLERİ TT - HDL Levels in Acute Miyocardial Infarction AU - Demirel, Serap PY - 1993 DA - March JF - Ankara Üniversitesi Tıp Fakültesi Mecmuası PB - Ankara University WT - DergiPark SN - 0365-8104 SP - 85 EP - 92 VL - 46 IS - 1 LA - tr AB - Serum total kolesterolünde artma, daha da önemlisi HDI, (high density lipoprotein) kolesterolünde azalma, yüksek koroner damar hastalığı (KDH) riski ile birliktedir. Çalışmalar koroner damar hastalığı riskini belirleyen en iyi göstergenin total kolesterol/HDIL kolesterol oranı olduğunu önermektedir. Ancak pekçok hekim, akut miyokardinfaktüsü sırasında hastanın kolesterol düzeylerine bakmamakta, bu değerleri elde etmek için birkaç ay beklemek eğilimindedir. Bu durum, KDH'nın ilerlemesine müdahale etmeyi geciktirmekte ya da engel olmaktadır.Sunulan çalışmada akut miyokard infaktüsü nedeniyle koroner bakım ünitesine yatırılan 162 hastada, ilk gün total kolesterol ve HDL kolesterol düzeyleri ölçüldü; total kolesterol/HDL kolesterol oranının hastaların yarıdan fazlasında çok yükselmiş olduğu belirlendi. KW - otal kolesterol KW - HDL (high density lipoprotein) kolesterol. KW - miyokard infaktüsü N2 - Increases in serum total cholesterol levels with decreased HDI. (high density lipoprotein) cholesterol are closely Linked with the increased incidence of coronary heart disease (CHD), especially the ratio of total cholesterol to HDL cholesterol being most significant. In practice, serum HDL cholesterol level measurements are usually postponed to months later after an initial myocardial infarction, This freguentiy causes delay or prevents initiation of patient management programs. In this study total cholesterol and HDL cholesterol of 162 patients with acute myocardial infarction were determined on the day of admission to the coronary care unit. The total cholesterol/HDL cholesterol ratio was found to be higher than normalin 9 50 of the patients. CR - 1. Ahnve S Angelin B Edhag © Berglund L : Early determination of serum lipids and apolipoprotiens in acute myocardial infarction ; Possibility for immediate intervention. J. Inter. Medicine 226 : 297-301, 1989. CR - 2. Ballantyne PC Clark RS Simpson HS Ballantyne D ; High density and low density lipoprotein subfractions in survivors of myocardial infarction and in control subjects. Metabolism 31 : 433-437, 1982. CR - 3. Cesarlo TC ; A symposium : Cardiovascular disease in the elderiy-etiology. prevention, diagnosis and treatment. Am, J. Cardio. 63 : 15, IH-59H, 1989, CR - 4. Dalen JE : Lowering serum cholesterol. It is time to proceed. Arch Intern Med 148 : 34-35, 1988. CR - 5. Dodds C Lond DSce, Mills GL ; Imfluence of myocardial infarction on plasmalipoprotein concentration. Lancet 6 : 1160-1163, 1959. CR - 6. dunn FL : Treatment of disorders in diabetes mellitus. Med CI North Am 72 : 1379-1399, 1988. CR - 7. Fyfe T Cochran KM Baxter RH Booth EM : Plasma-lipid changes after myocardial infarction, Lancet 6 : 997-1001, 1971. CR - 8. Goodman De WS ; Report of the national cholesterol education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults. Arch Intern Med 148 ; 36-69, 198. CR - 9. Core JM Goldberg RJ Matsumoto AS Casteli WP MecNamara PM Dalen JE ; Validity of serum total cholesterol level obtained within 24 hours of acute myocardial infarction. Am J Cardio 54 : 722-725, 1984. ' CR - 10. Gordon DJ Probstfield JL Garrison RJ Neaton JD Castelli WP Knoke JD Jacobs DR Bangdiwala 5 Tyroler HA : High-density lipoprotein cholesterol and cardiovascular disease, Four prospective American Studies, Circuletion 79 : 8-15, 1989. CR - 11. Grundy SM ; A symposium : Laboratory lipid values, Am J Cardio 56 : 1J-23J, 1985. CR - 12. Havel RJ Symposium on lipid disorders. Med CI North America, 66 : 375-441, 1982. CR - 13. Nestruck AC Davignon J ; Risk ol hiperlipidemia. Cardiology Clinics. 4 : 47-57, 1986. CR - 14. Nikkila M Koivula T Niemela K Sisto T : High density lipoprotein cholesterol and triglicerides as markers of angiographically assessed coronary artery diesase, Br Heart J 63 :78-81, 1990, CR - 15. Oliver MF : Why measure cholesterol after myocardial infarction and when? Br Med J 289 : 1641-1642, 1984, CR - 16. Tıbblin G Cramer K : Serum lipids during the course of an acute myocardial infarction and one year afterwards. Acta Medica Scandinavica, 174 : 451-455, 1963. CR - 17. Watson WC Buchanan KD Dickson C : Serum cholesterol levels after myocardial infarction. Br MedJ2i: 709-712, 1963. CR - 18. Witztum Juliano J : Intensive combination drug therapy of familial hypercholesterolemia with lovastatin, probucil and colestipol hydrochloride Circulation 79 : 16-28, 1989. UR - https://dergipark.org.tr/en/pub/autfm/issue//1721661 L1 - https://dergipark.org.tr/en/download/article-file/4967975 ER -