@article{article_1723402, title={Mesenteric Panniculitis and Systemic Inflammation: A Retrospective Analysis of Inflammatory Indices}, journal={Sanatorium Medical Journal}, volume={1}, pages={90–95}, year={2025}, author={Uysal Ramadan, Selma and Ertaş, İzzettin and Kaplan, Gökberk and Öztürk, Cansu and Çevik, Yunsur}, keywords={Mesenteric panniculitis, Computed tomography, NLR, PLR, SII, AISI, systemic inflammatory response}, abstract={Introduction: Mesenteric panniculitis (MP) is a nonspecific inflammatory pathological condition affecting the mesenteric adipose tissue. Data regarding systemic inflammatory markers in patients with MP are limited. This study aimed to investigate the relationship between tomographic findings of MP and systemic inflammatory blood parameters obtained from complete blood count (CBC), and to evaluate their correlation with the severity of MP. Materials and Methods: This was a retrospective study. Patients aged 18 years and older who underwent abdominal CT scans for any reason and had concurrent comprehensive laboratory tests between January 1, 2015, and January 1, 2020, were included. Demographic data and laboratory findings were reviewed. White blood cell count, hemoglobin, neutrophil count, lymphocyte count, platelet count, platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), systemic inflammatory response index (SIRI), systemic immune-inflammation index (SII), and aggregate index of systemic inflammation (AISI) were evaluated. MP severity was scored between a minimum of 3 and a maximum of 15 points, and classified as mild (score 3–5), moderate (score 5–9), and severe (score 10–15). Results: A total of 80 patients were included in the study. The median total MP score was found to be 6. Among the patients, 36.2% were classified as mild, and 63.8% as moderate-to-severe. When patients were evaluated according to the severity of mesenteric panniculitis, no statistically significant differences were found in comorbidities or systemic inflammatory parameters (p > 0.05 for all values). Conclusion In patients with mesenteric panniculitis (MP), in the absence of accompanying acute or chronic infectious or inflammatory pathologies, it does not appear to affect the systemic inflammatory response.}, number={2}, publisher={T.C. Sağlık Bakanlığı Ankara Atatürk Sanatoryum Eğitim ve Araştırma Hastanesi}