TY  - JOUR
T1  - Mesenteric Panniculitis and Systemic Inflammation: A Retrospective Analysis of Inflammatory Indices
AU  - Ertaş, İzzettin
AU  - Uysal Ramadan, Selma
AU  - Kaplan, Gökberk
AU  - Öztürk, Cansu
AU  - Çevik, Yunsur
PY  - 2025
DA  - September
Y2  - 2025
JF  - Sanatorium Medical Journal
JO  - Sanatorium Med J
PB  - T.C. Sağlık Bakanlığı Ankara Atatürk Sanatoryum Eğitim ve Araştırma Hastanesi
WT  - DergiPark
SN  - 3062-3944
SP  - 90
EP  - 95
VL  - 1
IS  - 2
LA  - en
AB  - Introduction:Mesenteric panniculitis (MP) is a nonspecific inflammatory pathological condition affecting the mesenteric adipose tissue. Data regarding systemic inflammatory markers in patients with MP are limited. This study aimed to investigate the relationship between tomographic findings of MP and systemic inflammatory blood parameters obtained from complete blood count (CBC), and to evaluate their correlation with the severity of MP.Materials and Methods:This was a retrospective study. Patients aged 18 years and older who underwent abdominal CT scans for any reason and had concurrent comprehensive laboratory tests between January 1, 2015, and January 1, 2020, were included. Demographic data and laboratory findings were reviewed. White blood cell count, hemoglobin, neutrophil count, lymphocyte count, platelet count, platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), systemic inflammatory response index (SIRI), systemic immune-inflammation index (SII), and aggregate index of systemic inflammation (AISI) were evaluated. MP severity was scored between a minimum of 3 and a maximum of 15 points, and classified as mild (score 3–5), moderate (score 5–9), and severe (score 10–15).Results:A total of 80 patients were included in the study. The median total MP score was found to be 6. Among the patients, 36.2% were classified as mild, and 63.8% as moderate-to-severe. When patients were evaluated according to the severity of mesenteric panniculitis, no statistically significant differences were found in comorbidities or systemic inflammatory parameters (p > 0.05 for all values).ConclusionIn patients with mesenteric panniculitis (MP), in the absence of accompanying acute or chronic infectious or inflammatory pathologies, it does not appear to affect the systemic inflammatory response.
KW  - Mesenteric panniculitis
KW  - Computed tomography
KW  - NLR
KW  - PLR
KW  - SII
KW  - AISI
KW  - systemic inflammatory response
CR  - 1.	Buragina G, Magenta Biasina A, Carrafiello G. Clinical and radiological features of mesenteric panniculitis: a critical overview. Acta Biomed. 2019;90(4):411-422.
CR  - 2.	Protin-Catteau L, Thiéfin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016;57(12):1438–1444.
CR  - 3.	Issa I, Baydoun H. Mesenteric panniculitis: various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14;15(30):3827–30.
CR  - 4.	Coulier B. Mesenteric panniculitis. Mesenteric panniculitis. Part 2: prevalence and natural course: MDCT prospective study. JBR-BTR. 2011;94(5):241–6.
CR  - 5.	Oztan MO, Ozdemir T, Uncel M, Diniz G, Koyluoglu G. Isolated omental panniculitis in a child with abdominal pain: case report. Arch Argent Pediatr. 2016;114(6):425.
CR  - 6.	Emektar E, Dağar S, Karaatlı RH, Uzunosmanoğlu H, Buluş H. Determination of factors associated with perforation in patients with geriatric acute appendicitis. Ulus Travma Acil Cerrahi Derg. 2022;28(1):33-38.
CR  - 7.	Özen Olcay H, Emektar E, Tandoğan M, Şafak T, Bulus H, Cevik Y, et al. Evaluation of urine analysis in adults with simple and complicated appendicitis. Ankara Med J. 2020;20:790-7.
CR  - 8.	Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing Mesenteritis, Mesenteric Panniculitis and Mesenteric Lipodystrophy: a single entity. The American Journal of Surgical Pathology. 1997;21(4):392–8.
CR  - 9.	Kaya C, Bozkurt E, Yazıcı P, İdiz UO, Tanal M, Mihmanlı M. Approach to the diagnosis and treatment of mesenteric panniculitis from the surgical point of view. Turk J Surg. 2018;34(2):121-124.
CR  - 10.	Scheer F, Spunar P, Wiggermann P, Wissgott C, Andresen R. Mesenteric Panniculitis (MP) in CT - A Predictor of Malignancy? 2016;188(10):926-932.
CR  - 11.	Horton K.M., Lawler L.P., Fishman E.K. CT findings in sclerosing mesenteritis (panniculitis)spectrum of disease. Radiographics. 2003;23:1561–1567.
CR  - 12.	Ming-En Zhao, Ling-Qiang Zhang, Li Ren, Zhen-Wei Li, Xiao-Lei Xu, Hai-Jiu Wang. A case report of mesenteric Panniculitis. J. Int. Med. Res. 2019;47(7):3354–3359.
CR  - 13.	Daskalogiannaki M, Voloudaki A, Prassopoulos P, Magkanas E, Stefanaki K, Apostolaki E, Gourtsoyiannis N. CT evaluation of mesenteric panniculitis: prevalence and associated diseases. AJR Am J Roentgenol. 2000;174:427–431.
CR  - 14.	Abdelwahed Hussein Mahmoud Rezk, Abdelwahed Saad Rezk. Mesenteric panniculitis: an update. Expet Rev. Gastroenterol. Hepatol. 2015;9(1):67–78.
CR  - 15.	Delgado Plasencia L, Rodríguez Ballester L, López-Tomassetti Fernández EM, Hernández Morales A, Carrillo Pallarés A, Hernández Siverio N. Paniculitis mesentérica: experiencia en nuestro centro [Mesenteric panniculitis: experience in our center]. Rev Esp Enferm Dig. 2007;99(5):291-297.
CR  - 16.	Atacan H, Erkut M, Değirmenci F, Akkaya S, Fidan S, Coşar AM. A Single Tertiary Center 14-year Experience with Mesenteric Panniculitis in Turkey: A Retrospective Study of 716 Patients. Turk J Gastroenterol. 2023;34(2):140-147.
UR  - https://dergipark.org.tr/en/pub/sanatoriummedj/issue//1723402
L1  - https://dergipark.org.tr/en/download/article-file/4975242
ER  -