TY - JOUR T1 - The effectiveness of low-dose intravenous ketamine on postoperative pain management in arthroscopic knee surgery under spinal anesthesia TT - Spinal anestezi altında artroskopik diz cerrahisinde düşük doz intravenöz ketaminin postoperatif ağrı yönetimindeki etkinliği AU - Özkavak, Dilşad AU - Yılmaz, Ayfer Nazmiye AU - Kılıç, Yeliz AU - Özkavak, Sadık AU - Göğüş, Nermin PY - 2025 DA - October Y2 - 2025 DO - 10.32322/jhsm.1724244 JF - Journal of Health Sciences and Medicine JO - J Health Sci Med /JHSM /jhsm PB - MediHealth Academy Yayıncılık WT - DergiPark SN - 2636-8579 SP - 1060 EP - 1064 VL - 8 IS - 6 LA - en AB - Aims: This study aimed to determine the efficacy of intraoperative low-dose intravenous ketamine on postoperative analgesia in patients who were underwent arthroscopic knee surgery under spinal anesthesia.Methods: Forty patients were equally classified as control and ketamine groups. In the ketamine group, 0.15 mg/kg intravenous ketamine was administered between 35-45. minutes of the surgery, whereas the patients in the control group received no medication. Postoperative pain was assessed using a visual analogue score. An analgesic, intravenous tramadol, was administered if the patients showed a value of at least 5 on the VAS. The need of first analgesic drug, the time to first analgesic drug administration, and additional (second and third) analgesic requirement during the postoperative period were compared between the groups.Results: All patients in the control group and 8 (40%) patients in the ketamine group required first analgesic drug (p KW - Arthroscopic knee surgery KW - ketamine KW - postoperative analgesia KW - spinal anesthesia N2 - Amaçlar: Bu çalışmanın amacı, spinal anestezi altında artroskopik diz ameliyatı geçiren hastalarda intraoperatif düşük doz (subanestetik) intravenöz (IV) ketaminin postoperatif analjezi üzerindeki etkinliğini belirlemektir.Yöntemler: Kırk hasta eşit olarak kontrol ve ketamin grupları olarak sınıflandırıldı. Ketamin grubuna ameliyatın sonuna doğru subanestetik doz ketamin (0,15 mg/kg bolus IV) uygulanırken, kontrol grubundaki hastalara hiçbir ilaç verilmedi. İlk analjezik ilaca duyulan ihtiyaç, ilk analjezik ilacın uygulanmasına kadar geçen süre ve postoperatif dönemde ek (ikinci) analjezik gereksinimi gruplar arasında karşılaştırıldı.Sonuçlar: Kontrol grubundaki tüm hastalar ve ketamin grubundaki 8 hasta (%40) postoperatif olarak ilk analjezik ilaca ihtiyaç duydu (p CR - Vadhanan P. Recent updates in spinal anesthesia-a narrative review. Asian J Anesthesiol. 2021;59(2):41-50. doi:10.6859/aja.202106_59(2).0001 CR - Ledesma I, Stieger A, Luedi MM, Romero CS. Spinal anesthesia in ambulatory patients. Curr Opin Anaesthesiol. 2024;37(6):661-665. doi: 10.1097/ACO.0000000000001412 CR - Dimaculangan D, Chen JF, Borzio RB, Jauregui JJ, Rasquinha VJ, Maheshwari AV. Periarticular injection and continuous femoral nerve block versus continuous femoral nerve block alone on postoperative opioid consumption and pain control following total knee arthroplasty: randomized controlled trial. 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