TY - JOUR T1 - Histopathological Investigation of the Effect of Intra-Arterial Dimethylsulfoxide on Ischemia/Rbpdfusion Injury Chapter - 111 TT - İskemi/Rbpdrfü'zyon Zedelenmesinde Intra Arteriyel Verilen Dımetilsülfoksitin Etkisinin Histopa70lojijk Olarak İncelenmesi Bölüm - 1111 AU - Egemen, Nihat PY - 1991 DA - September JF - Ankara Üniversitesi Tıp Fakültesi Mecmuası PB - Ankara University WT - DergiPark SN - 0365-8104 SP - 413 EP - 424 VL - 44 IS - 3 LA - en AB - In the experimentally foot)l cerebral ischemia/ recirculation ischemia Jhe effect cf intra arterial administration of the DM S O during the recirculation period to the ischemic lesion field have been evaluateci histcž)athoiogiaeolly, in rabbits. DMSO administred during pecirculEEion period is £ound to be beneficial effect in reducing ischemia. KW - iskemi KW - sinir KW - histopatoloji N2 - Deneysel fokal serebral iskemi/resirkülasyon iskemisinde resirkülasyonla beraber intra arteriel olarak verilen DiMetil Sülfoksit (DMSO)'in lezyon bölgesine olan etkileri histopatolojik olarak incelenmiştir. Resirkülasyon periyodunda intra arteriyel olarak verilen DMSO'nun iskemik değişikliklerin azaltılmasında faydalı etkisi oldüğü görülmüştür. CR - 1. De IA Torre JC : Sulfcxide in Prostoglandin-Tromboxane and Platelet Systems after Cerebral ischemia. Ann, NY Sci., 411 : 293 •308, 1983. CR - 2. EalkYcy GE : Free Radical-Modiated Puen)er£usion Injury : A Selective Review Par.. J. Cancer (Supp) 8 : 66-73, 1907. CR - 3. ES Pietronigro DD and Seligman ML : The Free Radical Pathology erycl the Microciì'i'ttlation in the Major Central Nervous System Acta Physial. Scan 492 : 91-120 *1930. CR - 4.G. I)ujov.n Rozario Dossovsky N Diaz FG and Segal R : Antiplatelet Effects of Dimethyl Barbiturates, and Metylprednisolone. Ann NY Acad Sci., 411 : 2343-244, 1983. CR - 5. Ikeda Y Anderson JH Long DIVI Oxygen Free Radicals in the Genesis of Traumatic PeriturnoraY Brain Oedemea. Neurosurgery 24 : 679-685, 1989. CR - 6. Ikeda Y and Kong DM : Comparative Effects of Direct and Indirect Hidroxyl Radica IScavengers on Travumatic Brain Oeclemea Acta Neurochi (Supp) 51 : 74-77, 1990. CR - 7. LW Povlïshock JT W Miller JD DP : The Role of Postigchemic Etecicculation in the Developmeny or Ischemic Neuronal Injury Followii3g Complete Cerobral ischemia. Acta Neuropathol. 55 : 205-220, 1981, CR - 8. Kedar J Jacop ET Bay-Na.tan and Ravid WI Dimethyl Sulfoyicle in Acut Ischemia of the Kidney. Ann. NY Acad Sci. • 41 : 131-134, 1983. - R. Hamroölu - CR - 9. KaJimo H Paljarvi L Olsson Y Siesjö BK : Structural Aspects of Energy Failure States in the Brain. in VViedemann Hoyer S. (eds). Problems and Perspectives of Brain Protection. Springer, Berlin Heidelberg, New York 1983, pp : 1-11. CR - 10. Kalimo H and Smith ML : Structural Aspect of Ischemic Brain Damage. Acta Neuroch. (Supp). 36 : 126„132, 1986. CR - 11. Kharacch N Thyagarajan BS Structural Basis for Biological Activities of Di metyl Sulfoxiclc. Ann. NY Acad. Sci, 411 : 391-402, 1983. CR - 12. Kolp KH ,Jaonicke G l{'ramo: M OL al : Absorption and Distribution aud Elimine,tion of Labeled Dimethyl Sull'o.gçide in Me.n and Animals Ann. NY, Accd. sci. 141 ; 85, 1967. CR - 13. P Mosl:owitz MA Levine, L Mclamcd E : The Synthessi of Prostaglandings by Bovine Cerebral Microvesse13. Prostagl. Mcd. 4 : 153-161, 1980. CR - 14. McC01d JM : Oxygen Derived Fžae Radicals in Postischemic Tissue injury. N Eng, J, Med. 312 (3) • 159-163, 1985. CR - 15. McGraw CP : Treatment of Cerebral Infarction with Dimethyl Sulfoxide in the Mongolian Gcrbil, Ann. NY Acad. Sci 411 278-283, 1983. CR - 16. Pace DG Kovacs JL Klevans LR : Dimetyl Su.lfoxide Inhibits Ann. NY. Acad. Sci, 411 : 352-355. 1963, UR - https://dergipark.org.tr/en/pub/autfm/article/1727127 L1 - https://dergipark.org.tr/en/download/article-file/4990370 ER -