TY - JOUR T1 - Mukoz Membran Pemfigoidi’nde Ağız Tabanı Tutulumu: Olgu Sunumu TT - Mucous Membrane Pemphigoid with Floor of Mouth Involvement: Case Report AU - Aydın, Can AU - Deniz, Müberra AU - Kırtıloğlu, Tuğrul AU - Akbari, Abbas PY - 2025 DA - August Y2 - 2025 DO - 10.21306/dishekimligi.1727479 JF - Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) JO - J Int Dent Sci PB - Zonguldak Bulent Ecevit University WT - DergiPark SN - 2149-8628 SP - 109 EP - 114 VL - 11 IS - 2 LA - tr AB - Amaç:Mukoz membran pemfigoidi (MMP), mukozal yüzeylerde subepitelyal büllerle seyreden nadir görülen otoimmün bir hastalıktır. Bu olgu sunumunun amacı, mukoz membran pemfigoidinin literatürde nadiren bildirilen ağız tabanı tutulumuna ve bu bölgedeki lezyonların tedavi sürecine dikkat çekmektir.Gereç ve Yöntemler:Diş eti kanaması ve periyodik büller şikâyetiyle kliniğimize başvuran 59 yaşındaki kadın hastada, ağız tabanı dahil olmak üzere yaygın oral tutulum mevcuttu. Yapılan detaylı klinik değerlendirme ve histopatolojik inceleme sonucunda MMP tanısı konulmuştur. Hastaya sistemik metilprednizolon, dapson ve mikofenolat mofetil içeren bir tedavi protokolü uygulanmıştır.Bulgular:Altı aylık takip sürecinde oral lezyonlarda belirgin gerileme ve klinik iyileşme gözlenmiştir. Tedaviye olumlu yanıt alınmıştır.Sonuç:Bu olgu, MMP’nin ağız tabanını da tutabileceğini göstermesi açısından önem taşımaktadır. Erken tanı ve uygun sistemik tedavi ile başarılı sonuçlar elde edilebileceği vurgulanmalıdır. KW - Ağız mukozası KW - ağız tabanı KW - büllöz lezyon KW - mukoz membran pemfigoid N2 - ABSTRACT:Objective:Mucous membrane pemphigoid (MMP) is a rare autoimmune disease characterized by subepithelial bullae on mucosal surfaces. The aim of this case report is to highlight the involvement of the floor of the mouth—a localization rarely reported in the literature—and the therapeutic approach for lesions in this region.Materials and Methods:A 59-year-old female patient presented to our clinic with complaints of gingival bleeding and periodic bullae. Clinical examination revealed extensive oral involvement, including the floor of the mouth. Following a thorough clinical evaluation and histopathological analysis, a diagnosis of MMP was established. The patient was treated with a systemic regimen consisting of methylprednisolone, dapsone, and mycophenolate mofetil.Results:During the six-month follow-up period, a marked regression of the oral lesions and clinical improvement were observed. 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UR - https://doi.org/10.21306/dishekimligi.1727479 L1 - https://dergipark.org.tr/en/download/article-file/4991916 ER -