TY - JOUR T1 - Türkiye'de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler TT - Characteristics And Etiological Factors Of Chronic Hepatitis In Turkey AU - Paykoç, Zafer PY - 1976 DA - September JF - Ankara Üniversitesi Tıp Fakültesi Mecmuası PB - Ankara University WT - DergiPark SN - 0365-8104 SP - 613 EP - 622 VL - 29 IS - 3 LA - tr AB - A. Ü. Tıp Fakültesi Gastroenteroloji Kliniğinde takip edilen kronik hepatit vak'a gurubu incelenerek Türkiye'de kronik hepatit etyolojisine yaklaşımda bulunulmuştur.40 Kronik hepatit vak'asında yapılan klinik, serolojik ve histopatolojik inceleme ile 9 kronik persistant hepatit, kronik aktiv hepatit örneği saptanmıştır. Vak'alarımızın tümünde HB ag positivliği % 47 bulundu bu oran kronik aktiv hepatitde % 51.0 kronik persistant hepa-UGUR KANDÌLCÌ — ÖZDEN UZUNALÏMOGLU ZAFER PAYKOÇtitde % 33.3 dür. Kronik aktiv hepatit vak'alarm yalnu 3 tanesi sistemik belirtileri ile Lupoid hepatit tipindedir. Bu bulgular ile memleketimizde Kronik hepatit vak'alarmm hemen yarlS1 HB ag (+) , sinsi seyirli sistemik belirtileri bulunmwan ve laboratuvarda orta derecede transmmaz) globilin yüksekliži ile karakterize vak'alar oldužunu göstermektedir. Etyolojide sorumlu ilâçlar, alkol, otoimmun mekanizma ile olusan kronik aktiv hepatit örnežinin memleketimizde oldukça nadir oldugu kamslndasnz. KW - hbv KW - akut hepatit KW - kronik hepatit N2 - 40 patients with chronic hepatitis were studied clinically, and histopatologically. These cases were diided into two groups. 9 of these cases proved to be persistant hepatitis, 31 of these to be chronic active hepatitis.In 47 % of he chronic hepatitis cases HB Ag was positiv. This relation was found 51 percent in the patients with chronic active hepatitis and 33 percent in chronic persistant hepatitis only 3 of all the chronic active hepatitis cases were lupold„ he patitis type.The results suggest thet in our cauntry aetiologically alc Alcohol hol, drugs, or autoimmun mechanisms is quite rare in pathogenesis of chronic hepatitis. CR - 1 — Groote J. D, Desmet V.J, Popper H, Schener P. A.A Classification of chronic hepatitis Lancet Il: 626,1968 CR - 2 — Popper H, Theproblemofhepatitis. Amer. J. Gastroenterology 55: 355, 1971 3 — Wright R. Chronic hepatitis. Brit. Med. Bull. 28; 120,197? CR - 13 — Mac Kay Ir, Weiden S, Hasker J. Autoimmun hepatitis. Ann NY Acad. sci 124 : 767, 1965 CR - 14 — Popper H, and MacKey IR: Ralation between Australia antigen and au- 15 — Soloway RD, Summershlll WHJ, Bagentoss AH ve ark. «Lupoid» hepatitis non entity In the spectrum of active chronic disease Gastroenterology 63: 458, 1972. 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