@article{article_1747748, title={Evaluation of Toxoplasmosis Serology Results and Test Request Dynamics in Ankara University Medical Faculty Hospitals}, journal={Ankara Üniversitesi Tıp Fakültesi Mecmuası}, volume={78}, pages={207–215}, year={2025}, DOI={10.65092/autfm.1747748}, author={Ulusan Bagci, Ozlem and Önder, Rabia and Akarsu, Gülay}, keywords={Anti-Toxoplasma IgM, anti-Toxoplasma IgG, positivity rate, immunocompromised, pregnant}, abstract={Background: Toxoplasmosis, caused by Toxoplasma gondii, is one of the most common parasitic diseases in the world and in our country. Serological methods are mainly used for diagnosis; however, there are some difficulties in the diagnosis of acute infection. Aim: The aim of this study was to evaluate the anti-Toxoplasma IgM and anti-Toxoplasma IgG results of serum samples sent to Ankara University İbni Sina Research and Training Hospital from various clinics, as well as the sociodemographic characteristics of the patients. Materials and Methods: Blood sample results from January 1, 2021, to September 1, 2024, were assessed. Anti-Toxoplasma antibodies were examined using the Elecsys kit in the Cobas device with the electrochemiluminescence immunoassay technique. Results: Anti-Toxoplasma IgG and IgM positivity rates were found to be 23.95% and 1.30%, respectively, between the specified dates. IgG results were positive in 21.54% of women and 30.48% of men. There was a statistically significant difference between the two genders (p <0.001). It was discovered that 1.19% of males and 1.34% of women had reactive anti-Toxoplasma IgM results; however, the difference was not statistically significant between the two genders (p=0.667). Most patients who tested positive for anti-Toxoplasma IgM and IgG were 80 years of age or above. Anti-Toxoplasma IgG positivity was highest in immunocompromised adult and pediatric clinics (44.06% and 42.21%, respectively); however, the adult infection service had the highest percentage (1.59%) for IgM positivity. Conclusion: Studies conducted in Türkiye revealed that the range of anti-Toxoplasma IgG positivity varied between 20.3% and 69.6%. Our study’s anti-Toxoplasma IgG positivity rate was between this range near the lower limit and consistent with prior studies conducted in Ankara. Studies in Türkiye have shown that IgM seropositivity varied from 0% to 9.7%. The anti-Toxoplasma IgM positivity ratio of our study was in this range and close to the lower limit similar to the anti-Toxoplasma IgG.}, number={3}, publisher={Ankara University}