TY  - JOUR
T1  - Ecballium Elaterium Meyve Usaresinin Kimyasal Analizi
TT  - Chemical Analysis of the Fruit Juice of Ecballium Elaterium
AU  - Akpoyraz, Mustafa
PY  - 1982
DA  - December
JF  - Ankara Üniversitesi Tıp Fakültesi Mecmuası
PB  - Ankara University
WT  - DergiPark
SN  - 0365-8104
SP  - 695
EP  - 700
VL  - 35
IS  - 4
LA  - tr
AB  - Bu çalışma, Türkiye’nin çeşitli bölgelerinde yetişen Ecballium elaterium bitkisinin (halk arasında eşekhıyarı olarak bilinir) meyvesinden elde edilen sıvının kimyasal yapısını incelemektedir. Özellikle anti-tümör etkileriyle bilinen cucurbitacin E (α-elaterin) adlı bileşik yüksek verimle izole edilmiş ve IR spektrumları ile erime noktaları literatür değerleriyle doğrulanmıştır. Ek olarak elaterin diasetat, elateridin, ekbalik asit ve tris-fenilhidrazon gibi türevleri elde edilmiştir. Ancak literatürde tanımlanan elaterisin A ve B bileşikleri başarılı şekilde izole edilememiştir. Elde edilen bileşiklerin deneysel anti-tümör etkilerinin ileri çalışmalarda değerlendirilmesi önerilmektedir.
KW  - kimya
KW  - meyve
KW  - analiz
N2  - This study investigates the chemical structure of the fluid extracted from the fruit of Ecballium elaterium (commonly known as squirting cucumber), which naturally grows in various regions of Turkey. The compound α-elaterin (cucurbitacin E), known for its anti-tumor effects, was successfully isolated in high yield and confirmed by IR spectra and melting point measurements consistent with literature data. Additionally, derivatives such as elaterin diacetate, elateridin, ecballic acid, and tris-phenylhydrazone were synthesized. Attempts to isolate elaterisin A and B, previously reported in the literature, were unsuccessful. Further experimental research is recommended to evaluate the anti-tumor activities of the isolated compounds.
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UR  - https://dergipark.org.tr/en/pub/autfm/issue//1748344
L1  - https://dergipark.org.tr/en/download/article-file/5080026
ER  -